after alzheimer disease, parkinson disease (pd) is considered the most common neurodegenerative disease. its prevalence is the same in all area but it is common in males than females. from every 100 persons who are above 60 years old, one of them has pd. also 5-10% of patients are less than 40 years old. this progressive neuroinflammation disease isn’t fatal. in 60% of cases is with depression....

background beta-2 microglobulin (b2m) is considered as a surrogate marker for middle molecule uremic toxins and a key component in dialysis-related amyloidosis. however, few studies have evaluated role of b2m in patients with chronic kidney disease (ckd). objectives the purpose of this study was to evaluate the association of plasma b2m level with some metabolic and cardiac performance factors ...

conclusions beliefs in health locus of control and type of illness in female patient group are predictors of illness acceptance (p = 0,0009). patients and methods three methods were applied: multidimensional health locus of control scale by k.a. wallston, b.s. wallston and r. devellis; the acceptance of illness scale by b.j. felton, t.a. revenson, and g.a. hinrichsena; and a personal questionna...

background: saffron (crocus satious l.) provides a variety of promising preventive and therapeutic effects with non-considerable side effects. objective: based on our knowledge, this is the first study that simultaneously has reviewed the effect of saffron extract and its constituents on the factors associated with neuropsychological, cardiovascular, and gastrointestinal tract diseases. methods...

how to cite this article: ghofrani m. lysosomal storage disease (lsds). iran j child neurol. 2015 autumn;9:4(suppl.1): 1. pls see pdf.

background there are few reports from iran about the epidemiology and clinical features of inflammatory bowel disease (ibd). this study aims to determine the epide­miologic profile and clinical features of ibd in northwest iran referral centers. methods in a cross-sectional setting, we evaluated 200 patients with definitive diagno­ses of ibd who referred to tabriz educational hospitals during t...

conclusions in cases of unusual vascular lesions, metabolic diseases must be considered. in homocystinuria, early diagnosis and treatment are important. blood homocysteine levels can be returned to normal, and some complications can be prevented. introduction homocystinuria is a hereditary disease caused by a defect in the enzymes involved in metabolizing methionine. homocystinuria can influenc...

thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. the pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (cams) and promoting the secretion of inflammatory chemokines and cytokines. dysregulated signaling functions of thro...

how to cite this article: karimzadeh p. pelizaeus-merzbacher- disease (pmd) and pelizaeus-merzbacher-like disease (pmld). iran j child neurol autumn 2014;8:4 (suppl.1):9-10.   pls see pdf.