There has been considerable recent interest in the suggestion that mineral fibres other than asbestos might be associated with mesotheliomas in the pleural and peritoneal cavities. Compared with the wealth of information on the consequences of exposure to asbestos, information about the effects of other fibrous minerals is sparse and much of it is of a preliminary nature. In this editorial the ...

There has been considerable recent interest in the suggestion that mineral fibres other than asbestos might be associated with mesotheliomas in the pleural and peritoneal cavities. Compared with the wealth of information on the consequences of exposure to asbestos, information about the effects of other fibrous minerals is sparse and much of it is of a preliminary nature. In this editorial the ...

BACKGROUND The bioavailability of natural food folates is lower than that of synthetic folic acid, but no agreement exists as to the extent of the difference. OBJECTIVE In a 4-wk dietary intervention study, we determined the aggregate bioavailability of food folates from fruit, vegetables, and liver relative to that of folic acid. DESIGN Seventy-two healthy adults were randomly divided into...

Considerable human-derived data the health consequences of asbestos exposure are available. Usually, less information is available from laboratory models of asbestos-related health effects. Animal data mirror the experience in man, and cellular studies help in to understand the mechanistic changes related to asbestos. Although it is clearly carcinogenic, asbestos has shown much variability when...

abstractbackground : the presence of primordial radionuclide in human habitats has always been a source of prolonged exposure. measurement of naturally occurring radionuclides in the environment can be used as baseline to evaluate the impact of non-nuclear activities and also routine releases from nuclear installations.   materials and methods: a total of 56 samples from 18 different foodstuff ...

Since 1998, the U.S. has mandated folic acid (FA) fortification of certain grain products to reduce the risk of neural tube defects. Folate intake and red blood cell (RBC) folate concentrations increased substantially post-intervention, although recent studies raise concerns about the level of ongoing benefit. This study investigated blood folate level determinants in healthy young adults, incl...

Folic acid is important because supplementation around the time of conception has been proven to lower the risk of having offspring with a neural-tube defect. Furthermore, both dietary folate and folic acid decrease plasma total homocysteine concentrations. Elevated plasma homocysteine concentrations are considered to be an independent risk factor for cardiovascular disease. The aim of the pres...

BACKGROUND Trilostane medical treatment of naturally occurring hyperadrenocorticism (NOH) in dogs is common, as is use of the adrenocorticotropic hormone (ACTH) stimulation test (ACTHst) in monitoring response to treatment. There is uncertainty regarding when the ACTHst should be started relative to time of trilostane administration. OBJECTIVE To compare ACTHst results in dogs being treated f...

BACKGROUND Folate dose-response studies in women of childbearing age who consumed a folic acid (FA)-containing multivitamin in the era of FA fortification are lacking. OBJECTIVE We sought to investigate folate-status response to a known folate dose comprising an FA-containing prenatal supplement (750 μg/d) plus natural food folate (400 μg/d) in third-trimester pregnant women, lactating women ...