PURPOSE An in situ forming hydrogel was evaluated as a potential vitreous substitute in rabbits. METHODS The hydrogel used a disulfide cross-linker that was then reduced to produce an injectable thiol-containing polymer solution. The disulfide cross-links reformed by air oxidation of the thiols and produced a stable hydrogel once inside the eye. The polymer was clear, autoclavable, and could ...

background : in recent years tissue engineering developed to replace or repair damaged tissues using cell and biomaterial. one of the most important fields of tissue engineering is simulation of in vivo micro environment of body tissues. this study aimed to develop culture chamber and cell biomaterial sheet engineering for the reconstruction of cartilage tissue. methods : stainless steel cultur...

Encapsulation of cells in hydrogel particles has been demonstrated as an effective approach to deliver therapeutic agents. The properties of hydrogel particles, such as the chemical composition, size, porosity, and number of cells per particle, affect cellular functions and consequently play important roles for the cell-based drug delivery. Microfluidics has shown unparalleled advantages for th...

Fibroblast cell cultivation method was evaluated by using natural polymers sourced from pulp cellulose in their hydrogel forms. The pulp sourced was offered as an alternative for the preparation of hydrogel films when the cellulose was dissolved in dimethylacetamide/lithium choride (DMAc/LiCl) solution and converted hydrogels having flexible and transparent properties. The cultivation of the fi...

Central Nervous System (CNS) repair has been a challenge, due to limited CNS tissue regenerative capacity. The emerging tools that neural engineering has to offer have opened new pathways towards the discovery of novel therapeutic approaches for CNS disorders. Collagen has been a preferable material for neural tissue engineering due to its similarity to the extracellular matrix, its biocompatib...

to reduce peat while increasing the water holding capacity (whc) of casing soil in button mushroom production an experiment was conducted in 2006 with three hydrogel treatments of: t0= casing soil with no hydrogel, as control, t1= casing soil + 10% hydrogel (v/v), and t2= casing soil + 20% hydrogel (v/v) with three replicates in a completely randomized design. results indicated that treatment 1...

Hydrogel is a polymer network system that can form hydrophilic three-dimensional structure through different cross-linking methods. In recent years, hydrogels have received considerable attention due to their good biocompatibility and biodegradability by introducing mechanisms functional components. Compared with synthetic hydrogels, natural polymer-based low biotoxicity, high cell affinity, gr...

A hydrogel exhibits a real-time depth-controllable swimming motion via light-mediated modulation of local density to mimic the volume changes found in the bladders of fish. Moreover, other motions, e.g., rolling, somersaulting, and bipedal-like walking, can also be realized by designing or combining gel shapes, and the location of light.

Responsive behavior, which is intrinsic to natural systems, is becoming a key requirement for advanced artificial materials and devices, presenting a substantial scientific and engineering challenge. We designed dynamic actuation systems by integrating high-aspect-ratio silicon nanocolumns, either free-standing or substrate-attached, with a hydrogel layer. The nanocolumns were put in motion by ...