background and objective: nasal polyp is the most common benign mass of the nasal cavity and it is originated from nasal cavity or sinuses. cytokeratins (ck) are intermediate filament proteins that provide mechanical support in epithelial cells. the purpose of this study was to compare the expression of cytokeratin 7 in epithelium of nasal polyps and nasal mucosa in chronic rhinosinusitis. mate...

background and objectives: nasal polyposis is a diseases resulting from complex pathogenetic mechanisms. some studies showed that tgfβ1 had significant role in this pathogenesis. in this study, we investigated the roe of cytokines and mediators in polyp development. material and methods: in this case- control study, healthy nasal mucosal samples were obtained from 24 people undergoing septoplas...

Nasal polyp is one of the common causes of nasal obstruction. The diagnosis is usually made on clinical ground and rarely needs histological examination. However, when a candidate is selected for the surgical option of polyp removal, there is tendency to send all specimens for routine histological examination. The objective of this study was to assess the necessity of routinely performed histol...

The role of stem cells (SCs) in the pathogenesis of nasal polyp (NP) is still controversial, while some researchers approved increase in stem cell count in nasal polyp, others denied this finding. Therefore, this project aimed at studying this phenomenon by using immunhistochemical (IHC) technique by which nestin-labelled stem cell can be identified and counted in normal people & nasal polyp pa...

BACKGROUND The prevalence of nasal polyp in the population has been estimated to be 0.5-4%. It is noticed that nasal polyp could have a negative impact on the patient's quality of life and indubitably exert a substantial cost on the society. It is observed that, in some cases, complete cure may not be achieved and relapse can occur. In Iranian traditional medicine (ITM), nasal polyp is called "...

Introduction: Nasal polyps are benign prolapsed mucosal lesions which commonly arise from the paranasal sinuses and lateral walls of the nose especially the contact areas of osteomeatal complex. Though nasal polyps arising from the nasal septum have been reported, those arising from its anterior part are extremely rare and present a diagnostic dilemma.  Aetiology is multifactorial and is mainl...

Choanal polyps are a form of nasal polyps that grow toward the choana with a single stalk. Septochoanal polyp is a rare entity that originates from the mucosa of the nasal septum with choanal extension. The most common site of its origin is mainly the superior aspect of the posterior portion of the nasal septum. However, metaplastic ossification is a rare event in nasal polyp and to the best of...

On histopathological examination, nasal polyps and nasal mucosa in allergic rhinitis show different forms of pseudostratified respiratory epithelium, whereas the dominant characteristic of lamina propria is an eosinophilic infiltration. The aim of this study was to compare interleukin (IL)-5 and eosinophilic cationic protein (ECP) levels in the nasal fluid of 42 patients: 12 with allergic rhini...

background: nasal polyps, a common clinical problem, are characterized by eosinophilic and mast cell inflammation.  the role of allergy and ige in pathogenesis of nasal polyps is still unclear.  ige receptors are important components of the immunological pathway in allergic and inflammatory diseases.   objective: to determine if the low affinity ige receptor (cd23) is presented on nasal polyp t...

Introduction: Angiectatic nasal polyp (ANP) is a rare entity of inflammatory sinonasal polyp, constituting 4 to 5% of all nasal polyps.1 An angiomatous polyp originates from a sinochoanal polyp, either an antrochoanal or a sphenochoanal polyp. Their hallmark feature is extensive vascular proliferation and ectasia with deposition of pseudoamyloid and the presence of atypical stromal cells. This ...