By adopting a ligand-based solid solution approach, the sulphonic acid functional group can be successfully incorporated into a porous coordination polymer with UiO-66 structure type. Zr(6)O(4)(OH)(4)(BDC-SO(3)H)(1.1)(BDC)(4.9) possesses enhanced heat of adsorption for carbon dioxide and acetone compared to Zr(6)O(4)(OH)(4)(BDC)(6).

Urinary and faecal excretion of radioactivity after either an intravenous or oral (1 mg/kg) dose of 35S-labelled Tobias acid (2-naphthylamino, 1-sulphonic acid), a dyestuff intermediate structurally similar to the powerful carcinogen 2-naphthylamine, was studied in rats. The Tobias acid was eliminated from the body within 24 hours of administration, almost exclusively through the urine. TLC-chr...

The effect of hydroxy substitution on 1,4-naphthoquinone toxicity to cultured rat hepatocytes was studied. Toxicity of the quinones decreased in the series 5,8-dihydroxy-1,4-naphthoquinone greater than 5-hydroxy-1,4-naphthoquinone greater than 1,4-naphthoquinone greater than 2-hydroxy-1,4-naphthoquinone, and intracellular GSSG formation decreased in the order 5,8-dihydroxy-1,4-naphthoquinone gr...

Aedes albopictus (Skuse) is a widespread mosquito, vector of important human arboviruses, including Chikungunya, Dengue and Zika. It an extremely difficult species to control even for the onset resistances chemicals insecticides, therefore ecofriendly products are urgently needed. In this study, activity Amaryllidaceae alkaloids some their semisynthetic derivatives, 2-methoxy-1,4-naphthoquinone...

The growth-inhibiting activity of Tabebuia impetiginosa Martius ex DC dried inner bark-derived constituents against Helicobacter pylori ATCC 43504 was examined using paper disc diffusion and minimum inhibitory concentration (MIC) bioassays. The activity of the isolated compounds was compared to that of the commercially available anti-Helicobacter pylori agents, amoxicillin, metronidazole, and t...

The antipruritic effects of orally administered 1,4-naphthoquinone derivatives and related compounds on compound 48/80-induced scratching behavior in mice were studied. 2-Hydroxy-3-(2-hydroxyethyl)-1,4-naphthoquinone, ferulic acid, 2,2'-methylenebis(3-hydroxy-1,4-naphthoquinone), and 2,2'-ethylidenebis(3-hydroxy-1,4-naphthoquinone) (impatienol) all exhibited significant antipruritic activity. H...

BACKGROUND Growing evidence suggests that intestinal recovery from injury induced by radiation, endotoxin, and protein deficiency is improved by the ingestion of nucleosides and nucleotides. AIM This study examined the effect of dietary nucleosides and nucleotides supplementation on trinitrobenzene sulphonic acid induced colonic damage in experimental colitis. METHODS Sprague-Dawley rats we...

In the present study, an appropriate synthetic route was adopted to produce the target synthesis of Juglone. In the first of these objectives, 5-nitro-1,4-naphthoquinone had been synthesized by direct nitration of 1,4-naphthoquinone in the presence of water and sulfuric acid. Then the intermediate synthesis of 5-amino-1,4-naphthoquinone was obtained by the reduction of nitro. Finally, Juglone w...