TB remains a global health challenge and, until now, only one licensed vaccine (the BCG vaccine) is available. The main goal of this work to assess the progress in development new vaccines and highlight research nanovaccines. A review was conducted using methodology with appropriate keywords inclusion exclusion criteria. search revealed 37 clinical trials that were further reviewed. results ava...

Type I natural killer T (NKT) cells have gained considerable interest in anticancer immune therapy over the last decade. This "innate-like" T lymphocyte subset has the unique ability to recognize foreign and self-derived glycolipid antigens in association with the CD1d molecule expressed by antigen-presenting cells. An important property of these cells is to bridge innate and acquired immune re...

vaccination has greatly improved human health. despite of all improvements in this field, there is not an efficient vaccine for many diseases, and of the available ones, some could not produce a long-term immunity. recently, there have been many researches on the applicability of nanostructures as an efficient system for vaccine delivery, and the initial results have been promising. their poten...

Aerobic Vaginitis In article number 202203028, Yongbin Mou, Zhaogang Teng, Heng Dong, and co-workers report a Ti3C2 MXene-based nanoplatform (MXP) with high-efficiency near-infrared photothermal conversion immunocompetent loading capacity to form endogenous/exogenous nanovaccines. The combined strategy by using MXPs, as nanoagents immune carriers, activates the DC-based antitumor cascade respon...