Abstract Triple‐negative breast cancer (TNBC) is the most aggressive subtype, which often results in distant metastasis and dismal prognosis. Unfortunately, current treatments for TNBC are not effective due to its resistance immunotherapy. Recent studies indicate that B7‐H4 immune checkpoint overexpression inflammation‐initiated neutrophil extracellular traps (NETs) closely associated with poor...

Nanotechnology is of intense interest to researchers due the basic fact that properties material can be effectively manipulated when size transformed nanoscopic. New opportunities arise out unique features which have been effectually utilized in development nano pharmaceuticals. This has revolutionized health care system extensively by its diverse applications modern medicine and dental science...

B lymphoblastic leukemia (B-LL) is a clonal hematopoietic stem cell neoplasm derived from B-cell progenitors, which mainly occurs in children and adolescents one of the main causes death malignant tumors this population. The surface marker CD19 specifically expressed on membrane most B-cells, widely used as B-LL antigen-specific immunotherapy. In study, mesoporous titanium dioxide nanoparticles...

Brain research is the most expanding interdisciplinary research that is using the state of the art techniques to overcome limitations in order to conduct more accurate and effective experiments. Drug delivery to the target site in the central nervous system (CNS) is one of the most difficult steps in neuroscience researches and therapies. Taking advantage of the nanoscale structure of neural ce...

The chemical structure of CyssTP and its self-assembly into a glutathione-activated carrier-free nanodrug triptolide (CyssTPN) as trackable drug delivery system for tumor therapy.

in this study, confined impinging liquid jets are used to produce nanoparticles of carbamazepine (cbz). the effect of operating parameters, such as the kind of solvent,cbz concentration, flow rate of solution and antisolvent on particle size, are experimentally investigated. the scanning electron micrograph (sem) photomicrographs show that nanodrug with smaller particle is achievable by using s...