BACKGROUND Megestrol acetate is an effective treatment for improving appetite and increasing body weight in patients with cancer-associated anorexia. However, Megace oral suspension (OS), a micronized formulation of megestrol acetate, has low bioavailability in the fasting state. To overcome this limitation, a nanocrystal formulation has been developed. This study was performed to evaluate the ...

This letter describes the fabrication and structural and electrical characterization of an aerosol-nanocrystal-based floating-gate field-effect-transistor nonvolatile memory. Aerosol nanocrystal nonvolatile memory devices demonstrate program/erase characteristics comparable to conventional stacked-gate nonvolatile memory devices. Aerosol nanocrystal devices with 0.2 mm channel lengths exhibit l...

The preparation of highly efficient perovskite nanocrystal light-emitting diodes is shown. A new trimethylaluminum vapor-based crosslinking method to render the nanocrystal films insoluble is applied. The resulting near-complete nanocrystal film coverage, coupled with the natural confinement of injected charges within the perovskite crystals, facilitates electron-hole capture and give rise to a...

Nucleic acid-based aptamers have been developed for the specific delivery of diagnostic nanoprobes. Here, we introduce a new class of smart imaging nanoprobe, which is based on hybridization of a magnetic nanocrystal with a specific aptamer for specific detection of the angiogenic vasculature of glioblastoma via magnetic resonance (MR) imaging. The magnetic nanocrystal imaging core was synthesi...

It is necessary to control the size, shape, and uniformity of self-assembled and self-organized nanocrystals in order to use them in real devices. The way to achieve this in epitaxial nanocrystal arrays is by manipulating the bulk stress and/or the surface stress. In this work, an additional and fundamentally different mechanism of CoSi2 nanocrystal size selection is reported, based on a prefer...

In this publication we show that the procedure to synthesize nanocrystals and the post-synthetic nanocrystal ligand sphere treatment have a great influence not only on the immediate performance of hybrid bulk heterojunction solar cells, but also on their thermal, long-term, and air stability. We herein demonstrate this for the particular case of spherical CdSe nanocrystals, post-synthetically t...

The charge retention characteristics of metal nanocrystal (MNC) and semiconductor nanocrystal (SNC) memory devices are comparatively studied in this paper. A charge retention model is proposed, taking into account the quantum confinement effect, to account for the better retention characteristics of metal nanocrystal memory observed in the experiment. Simulation results are in good agreement wi...

Improving devices incorporating solution-processed nanocrystal-based semiconductors requires a better understanding of charge transport in these complex, inorganic-organic materials. Here we perform a systematic study on PbS nanocrystal-based diodes using temperature-dependent current-voltage characterization and thermal admittance spectroscopy to develop a model for charge transport that is ap...

Small molecules with functional groups can show different electron affinity and binding behavior on nanocrystal surface, which in principle could be used to alternate the electrical transport in self-assembled nanocrystal thin films. These small molecules can also serve for scattering the phonons to reduce the thermal conductivity. Here, we present our research on the thermoelectric characteris...

T he properties of materials often change drastically when their size is decreased to the nanometre range. For example, as the surface-to-volume ratio of a material is increased, typically its melting temperature depresses and its chemical reactivity tends to increase. Also, as the size of a crystal shrinks down to submicrometre sizes, it becomes more difficult to deform it plastically (that is...