Developing a nanobiosensor for non-invasive visualization of the AKT signaling pathways Amnon Bar-Shir, Nikita Oskolkov, Galit Pelled, Jeff W.M. Bulte, Michael T McMahon, and Assaf A. Gilad Radiology, Johns Hopkins University, Baltimore, MD, United States, Institute for Cell Engineering, Johns Hopkins University, Baltimore, MD, United States, F.M. Kirby Research Center, Kennedy Krieger Institut...

Electrochemical biosensor holds great promise in the biomedical area due to its enhanced specificity, sensitivity, label-free nature and cost effectiveness for rapid point-of-care detection of diseases at bedside. In this review, we are focusing on the working principle of electrochemical biosensor and how it can be employed in detecting biomarkers of fatal diseases like cancer, AIDS, hepatitis...

Nanotechnology is the manipulation of material on an atomic and molecular scale; by changing its physical, chemical and biological properties to produce novel materials, devices, and systems. Nanomaterials exhibit remarkable characteristics such as high surface to volume ratio, catalytic activity, and biocompatibility which make them suitable for various biomedical applications. Nanotechnology ...

Cortisol plays an important part in physiological procedures. Observing cortisol concentration as a stress indicator demonstrates the mode for diagnosis goal. The mechanism of presented nano biosensor is LSPR and performed based on nucleic acid aptamer functionalized with gold nanoparticles which have specific interaction cortisol. particular measurement was accomplished over from 0.05 -0.2 μg·...

Nanosensors can be defined as sensors based on nanotechnology. The aim of some nanobiosensor projects at potentially high volume applications in the public health sector, as preventing food poisoning where markets might be significant, while the other aim to improve on existing clinical practises by allowing the more quantification and rapid detection of bacteria and viruses. It should increase...

We present a technique for the label-free detection and recognition of cancer biomarkers using metal nanoislands intended to be integrated in a novel type of nanobiosensor. His-tagged (scFv)-F7N1N2 is the antibody fragment which is directly immobilized, by coordinative bonds, onto ~5 nm nickel islands, then deposited on the surface of a quartz crystal of a quartz crystal microbalance (QCM) to v...