BACKGROUND Polymers are attractive materials for both biomedical engineering and cardiovascular applications. Although nano-topography has been found to influence cell behaviour, no established method exists to understand and evaluate the effects of nano-topography on polymer-blood interaction. RESULTS We optimized a micro-fluidic set-up to study the interaction of whole blood with nano-struc...

The basic building blocks of nano-structured hierarchical cellular materials are nano-sized wires or plates. Due to the effects of surface elasticity and the initial stress/strain, their bending, torsion, stretching and transverse shear rigidities are not only size-dependent, but also tunable and controllable over a large range. Based on the closed form results of the bending, torsion, stretchi...

Over the last three decades there has been significant progress in the first principles methods for calculating the properties of materials at the quantum level. They have largely been based on the local density approximation (LDA) to density functional theory (DFT). However, nanoscience places new demands on these first principles methods because of the thousands to millions of atoms present i...

Fabrication of nano-structured materials has been developed by performing pulsed laser ablation of copper, gold, and silver plates in supercritical CO2. The metal nano-structured particles were successfully generated with allowing the selective generation of clusters. Laser ablation was performed with an excitation wavelength of 532 nm. On the basis of the experimental result, both surface of a...