introduction : the encapsulation of nutraceuticals in lipid based carriers, such as liposomes, can lead to increasing of bio-active ingredients bioavailability and controlled release, maintaining their stability in different environmental conditions and increasing solubility of hydrophobic active ingredients in aqueous conditions. food grade liposomes are being increasingly used in food industr...

Liposomes are the first nano drug delivery systems that have been successfully translated into real-time clinical applications. These closed bilayer phospholipid vesicles have witnessed many technical advances in recent years since their first development in 1965. Delivery of therapeutics by liposomes alters their biodistribution profile, which further enhances the therapeutic index of various ...

in-vitro labeling of rbc with 99mtc is an intricate procedure and there is always a need foran alternate blood pool imaging agent. the aim of this study was to prepare an effective nanosized liposome (nls) similar to human rbc for blood pool scintigraphy. this study formulatespeg-nls and non-peg-nls using film method plus high pressure homogenization technique.biodistribution studies were perfo...

(DDC)2Zn, disulfiram (DS) metabolite, has shown promisinganticancer effects in vitro but further investigations vivo are limited by itspoor water solubility. In this study, liposomes assessed as a deliverysystem for (DDC)2Zn. Liposomes were prepared the thin-filmhydration method, followed high-pressure homogenisation (HPH) sizereduction. The nano-liposomes then characterised size, polydispersit...

The Effect of Exercise and Folate Nano-Liposomes on D1 D2 Receptor Gene Expression in the Brain Alzheimer's Rats

BACKGROUND The purpose of this study was to formulate and evaluate nano lipid vesicles of methotrexate (MTX) for its anti-rheumatoid activity. METHODS In this study the principle of both active as well as passive targeting using MTX-loaded stealth liposomes as per the magic gun approach was followed. Stealth liposomes of MTX were prepared by thin-film hydration method using a PEGylated phosph...

Improving the Quality of Rooster Sperm during Storage at 4 °C by adding Quercetin in form nano-Liposomes and NLC a Diluting Medium

results at high concentrations (40 and 100 μm), apoptosis was demonstrated and it was clearly more prominent in hepatocytes exposed to celecoxib loaded liposomes. conclusions our results showed that celecoxib loaded liposomes robustly induced apoptosis, an action that can potentially make it more relevant than the usual form for chemopreventive strategies and also may raise concerns about its t...

Nano carrier systems were prepared by forming self-assembled liposomes having a size distribution in the nano range through use of an ultrasonic homogenizer. Phosphatidylcholine and cholesterol were utilized as an amphiphilic compound and a shape stabilizer, respectively. The size of prepared samples was decreased (up to 150 nm) by elevating ratio of lecithin and extending homogenization time (...

BACKGROUND Cancer remains a leading cause of death in companion animals. In human medicine, liposomes and nanoparticles have been extensively investigated as drug delivery systems (DDS) for anticancer agents due to their ability to target cancerous cells and reduce the negative side effects of free cytostatic drugs. In this review, the authors discuss the results of clinical trials using liposo...