نتایج جستجو برای: nadh
تعداد نتایج: 9100 فیلتر نتایج به سال:
با توجه به نقش مهمی که کوآنزیم nadh (-b نیکوتین آمید آدنین دی نوکلئوتید) در متابولیسم، انتقال الکترون در واکنشهای تولید انرژی و بیوسنتز در بدن موجودات زنده دارد اندازه گیری آن از اهمیت خاصی برخوردار است . در این تحقیق نتایج حاصله از بررسی و بهینه سازی یک روش سینتیکی اندازه گیری کوآنزیم nadh با استفاده از اسپکتروفتومتری ارائه می گردد. این روش براساس واکنش اکسیداسیون کوآنزیم nadh، در حضور آنزیم پ...
Abstract The electrochemical regeneration of the reduced form nicotinamide adenine dinucleotide cofactor (NADH) was realized in a hybrid flow reactor coupling fuel cell technology and redox device, paying attention to robust immobilization all catalysts. rhodium catalyst Rh(Cp✶)(bpy)Cl + covalently immobilized on multi‐walled carbon nanotube (MWCNT) layer association with gas diffusion electrod...
There is no comprehensive method for differentiating between fresh and frozen-thawed fish fillets. This an ongoing problem, particularly in relation to regulations. In this study, we showed the relevance of using properties mitochondria discriminate fillets from The use red muscle fibres Gilthead sea bream allowed us leave their physiological environment avoid possible alterations mitochondrial...
NADH:ubiquinone oxidoreductase, respiratory complex I, plays a central role in cellular energy metabolism. As major source of reactive oxygen species (ROS) it affects ageing and mitochondrial dysfunction. The novel inhibitor NADH-OH specifically blocks NADH oxidation ROS production by I nanomolar concentrations. Attempts to elucidate its structure NMR spectroscopy have failed. Here, using X-ray...
In this study, we investigated the properties of mitochondria to discriminate fresh from frozen-thawed fish fillets. Mitochondria were isolated gilthead seabream fillets and impact freezing was evaluated by measuring permeability mitochondrial membranes. Freezing led permeabilization inner membranes reduced nicotinamide adenine dinucleotide (NADH). The increase in related shock compared physiol...
Hybrid Chemo-, Bio-, and Electrocatalysis for Atom-Efficient Deuteration of Cofactors in Heavy Water
Deuterium-labeled nicotinamide cofactors such as [4-2H]-NADH can be used mechanistic probes in biological redox processes and offer a route to the synthesis of selectively [2H] labeled chemicals via biocatalytic reductive deuteration. Atom-efficient routes formation recycling are therefore highly desirable but require careful design order alleviate requirement for [2H]-labeled reducing agents. ...
بیماری مالتیپل اسکلروزیس (multiple sclerosis) که به اختصار به آن ام اس (ms) گفته می شود از شایعترین بیماریهای مزمن ژنتیکی سیستم اعصاب مرکزی (مغز و نخاع) در سنین جوانی می باشد.در واقع ms یک بیماری مزمن اتوایمیون با واسطه سلولهای t است و در اثر عوامل ناشناخته در یک موجود با وجود زمینه ژنتیکی شروع می شود و از ویژگی های اصلی آن میتوان به التهاب، تخریب میلین و افزایش سلولهای گلیال اشاره کرد.در مناطق...
ei Zheng ong Li ianan Y. Qu ong Kong University of Science and Technology epartment of Electronic and Computer Engineering lear Water Bay, Kowloon ong Kong, China Abstract. Reduced nicotinamide adenine dinucleotide NADH is a well-known metabolic coenzyme and endogenous fluorophore. In this study, we develop a system that simultaneously measures timeand wavelength-resolved fluorescence to extrac...
The specific activity of plant NADH-dependent glutamate synthase (NADH-GOGAT) in root nodules of Phaseolus vulgaris L. is over threefold higher than the specific activity of ferredoxin-dependent GOGAT. The NADH-GOGAT is composed of two distinct isoenzymes (NADH-GOGAT I and NADH-GOGAT II) which can be separated from crude nodule extracts by ion-exchange chromatography. Both NADH-GOGAT isoenzymes...
Nicotinamide adenine dinucleotide (NADH) plays a major role in cellular metabolism and mitochondrial dysfunction and is thought that NAD+/NADH decrease neuronal degeneration and improve behavioral deficits. This potential use of NAD+ or NADH as neuroprotective drugs requires an insight on the pharmacokinetic properties of these compounds. For this reason, we assessed the absorption of NADH in t...
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