نتایج جستجو برای: n8
تعداد نتایج: 384 فیلتر نتایج به سال:
To determine whether alterations in the "reverse" or "conversion" pathway for putrescine formation were involved in the induction of colonic tumors by 1,2-dimethylhydrazine, male albino rats of the Sherman strain were given injections s.c. of this agent (20 mg/kg body weight/week) or diluent for 5, 10, 15, and/or 26 weeks. Animals were sacrificed at each of these time periods and polyamine leve...
Frequent infusions of intravenous factor VIII (FVIII) are required to prevent bleeding associated with hemophilia A. To reduce the treatment burden, recombinant FVIII with a longer half-life was developed without changing the protein structure. FVIII-polyethylene glycol (PEG) conjugates were prepared using an enzymatic process coupling PEG (ranging from 10 to 80 kDa) selectively to a unique O-l...
Dengue virus (DENV), a global disease, is divided into four serotypes (DENV1-4). Cross-reactive and non-neutralizing antibodies against envelope (E) protein of DENV bind to the Fcγ receptors (FcγR) of cells, and thereby exacerbate viral infection by heterologous serotypes via antibody-dependent enhancement (ADE). Identification and modification of enhancing epitopes may mitigate enhancement of ...
Single-atom catalysts show a promising future in many reactions even though great challenges still remain such as facile synthesis and long stability. In this work, single-atom Pd catalyst attached to designed N8 Lewis base species (Pd1-N8/CNT) is synthesized with cyclic voltammetry (CV) method. The demonstrates stability enhanced C2H4 selectivity selective hydrogenation of acetylene at 40 °C. ...
Crosslinkable hole transport materials (HTMs) with high triplet energies would have a balance of carrier injection into the emitting material layer, suppressing exciton quenching and resulting in high-performance solution-processed organic light-emitting diode (OLED) devices. Two novel crosslinkable HTMs different central units, N2, N8-di-p-tolyl-N2,N8-bis(4-vinylphenyl)dibenzo[b,d]thiophene-2,...
introduction: hospitalized children are often at increased risk of nutritional impairment at or during admission. objectives: the aims of this study were to (1) define the nutritional state of hospitalized children with comparison to healthy children in two different countries and (2) compare and contrast three nutritional risk screening (nrs) tools for hospitalized children in terms of the e...
The pretreatment concentrations of polyamines were determined in the 24-hr urine of 14 patients with widespread non-Hodgkin's lymphoma. In ten of 14 patients, the ratio of N1-acetylspermidine to N8-acetylspermidine was significantly higher than the mean for normal subjects. These results confirm our previous observations that the urinary excretion of N1-acetylspermidine is increased in some pat...
Enzymatic ribosylation of fluorescent 8-azapurine derivatives, like 8-azaguanine and 2,6-diamino-8-azapurine, with purine-nucleoside phosphorylase (PNP) as a catalyst, leads to N9, N8, and N7-ribosides. The final proportion of the products may be modulated by point mutations in the enzyme active site. As an example, ribosylation of the latter substrate by wild-type calf PNP gives N7- and N8-rib...
The current density-luminance-voltage characteristics of organic light-emitting devices ~OLEDs! with N ,N8-Bis~naphthalen-1-yl)-N ,N8-bis~phenyl! benzidine ~NPB! of various thicknesses as the hole transport layer have been investigated. It is found that for conventional structures of indium– tin–oxide/NPB/tris~8-hydroxyquinoline! aluminum (Alq3) ~60 nm!/LiF ~0.5 nm!/Al the optimal hole injectio...
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