In the title compound, [Cu(NO(3))(2)(C(5)H(6)N(2))(4)], the Cu(II) ion is located on an inversion centre. It features a Jahn-Teller-distorted octa-hedral coordination geometry, defined by four N atoms of four 1-vinyl-imidazole ligands in the equatorial plane and two nitrate O atoms in the axial positions. The nitrate anion is disordered over two sets of sites in a 0.801 (6):0.199 (6) ratio. In ...

The reaction of hexafluorothioacetone dimer (2,2,4,4-tetrakis(trifluoromethyl)-1,3-dithiethane, 1) with vinylamides leads to the rapid formation of [2 + 2] cycloadducts: 4-amino-2,2-bis(trifluoromethyl)thietanes. The reaction proceeds in polar solvents (DMF, DMSO) in the absence of a catalyst at elevated temperature producing the corresponding cycloadducts in 47-86% yield. The reaction of N-vin...

Reaction of nitroalkenes or nitrodienes with methyl vinyl ketone (MVK) or acrylate in the presence of the imidazole-LiCl catalyst system provides Rauhut-Currier (vinylogous Morita-Baylis-Hillman) adducts in moderate yield. Under similar conditions (imidazole-hydroquinone), nitroalkenes and nitrodienes undergo self-dimerization to afford the Rauhut-Currier adducts in varying yields. An alternati...

The Morita-Baylis-Hillman (MBH) adducts of beta-aryl nitroethylenes with methyl vinyl ketone (MVK) and acrylate, formed in moderate to good yield when mediated by imidazole/LiCl in THF at room temperature, inhibit HeLa cell proliferation by binding to tubulin.

in view of potential biological activities of small molecule polyamides, we synthesized some novel n-(2-aminoethyl)-1-benzyl-2- (alkylthio)-1h-imidazole-5-carboxamide (7a,b), and n-(2-(1-benzyl-2-(alkylthio) -1h-imidazole- 5-carboxamido) ethyl)-1-benzyl-2- (alkylthio)-1h-imidazole-5-carboxamides (8a,b) as antitumor agents. the antitumor activity of compounds 7a,b and 8a,b was studied at concent...

In the present study, molecularly imprinted polymers were synthesized using caffeic acid (CA) as a template molecule and then used for extraction of CA chlorogenic (CLA) from complex matrices. Syntheses carried out in tetrahydrofuran porogenic solvent 4-vinyl pyridine, methacrylic acid, acrylamide, 1-vinyl imidazole monomers, ethylene glycol dimethacrylate crosslinker 2,2'-azobisisobutyronitril...

      In view of potential biological activities of small molecule polyamides, we synthesized some novel N-(2-aminoethyl)-1-benzyl-2- (alkylthio)-1H-imidazole-5-carboxamide (7a,b), and N-(2-(1-benzyl-2-(alkylthio) -1H-imidazole- 5-carboxamido) ethyl)-1-benzyl-2- (alkylthio)-1H-imidazole-5-carboxamides (8a,b) as antitumor agents. The antitumor activity of compounds 7a,b and 8a,b was studied at c...

Poly(N-vinyl imidazole) (PVI) has been grafted onto carboxymethyl starch (CMS) in aqueous solution using potassium persulfate (KPS) as initiator. Reaction parameters that affect grafting efficiency and percentage grafting such as monomer and initiator concentration, the reaction temperature and time were investigated. The grafted products were characterized by FTIR, thermal analysis, SEM photog...