Erythromelalgia is a rare disorder frequently associated with myeloproliferative disorders. We describe a case of elderly patient diagnosed with myeloproliferative disorder in remission. The patient was on aspirin for secondary prevention of stroke and was taken off aspirin and developed erythromelalgia within two weeks of withdrawal of aspirin. After restarting aspirin, patient's symptoms impr...

By D. L. DUNGwORTH, NI. GOLDMAN, J. W. SWITZER AND D. H. MCKELVIE T HE TERM “MYELOPROLIFERATIVE DISORDER” was introduced by 2 to embrace a complex array of diseases characterized by irreversible proliferation of one to several of the bone marrow cell lines, and includes such conditions as granulocytic leukemia, myelofibrosis with myeloid metaplasia, polycythemia vera and erythremic myelosis. Th...

The pathogenesis of myeloproliferative disorder remains unknown, but there have been some experiments on murine myeloproliferative sarcoma induced by certain viruses. Myeloproliferative sarcoma virus which is well known among such viruses, causes myeloproliferative disorder in mice and today's work will reveal tumorigenicity of this virus in rats. Two groups of Jar-2 rats (31 young rats and 28 ...

By D. L. DUNGwORTH, NI. GOLDMAN, J. W. SWITZER AND D. H. MCKELVIE T HE TERM “MYELOPROLIFERATIVE DISORDER” was introduced by 2 to embrace a complex array of diseases characterized by irreversible proliferation of one to several of the bone marrow cell lines, and includes such conditions as granulocytic leukemia, myelofibrosis with myeloid metaplasia, polycythemia vera and erythremic myelosis. Th...

Spinal cord compression due to extramedullary hematopoiesis is a well-known complication in a number of hematological diseases. Most of the patients present with progressive paraparesis due to the slow expansion of the extramedullary hematopoietic tissue. The authors report a case of chronic myeloproliferative disorder with spinal extramedullary hematopoiesis presenting with acute paraplegia. C...

Chronic myelogenous leukemia (CML) is a myeloproliferative disorder that normally presents in middle-aged adults. Renal infiltration and extramedullary hematopoiesis in renal tissue has been rarely reported. This case report presents a patient with CML and renal insufficiency who developed gross hematuria. Efforts at controlling the hematuria led to a cascade of events propelled by the underlyi...

Essential thrombocythemia is a rare myeloproliferative disorder in pediatrics. This myeloproliferative disorder is charactherized by thrombocytosis and hyperplasia of megakaryocytes in the bone marrow. Other cell lines are not involved. JAK2V617F mutation has been identified in approximately half the patients with this disorder. We describe a 12-year-old boy with essential throbocythemia. The p...

Recent mathematical models have been developed for the Acute myeloid Leukaemia and myeloproliferative disorder. In this paper system of ODE is modelled. With help model we proposed necrotic core which develops in progression disease where cell subjected to accidental death that leads inflammation.