نتایج جستجو برای: myeloperoxidase mpo
تعداد نتایج: 7529 فیلتر نتایج به سال:
Although the pathogenesis of ankylosing spondylitis (AS), which is a systemic disease characterized by inflammation, largely unknown, pro-inflammatory mediators, oxidative stress, and immunity are thought to be involved in development prognosis disease. It was aimed this study reveal activities adenosine deaminase (ADA), cornerstone enzyme different pathways. Twenty nine AS patients 16 healthy ...
Myeloperoxidase (MPO) is an essential component of inflammatory response in norm and pathology. With an ultimate goal of non-invasive imaging of MPO we used a gadolinium-chelating bis(5-hydroxytrytamide) derivative of diethylenetetraamine pentaacetic acid (L1-Gd3+ salt) as a paramagnetic sensor of enzymatic activity. We tested whether L1-Gd3+ is active in reducing the oxidized form of myelopero...
OBJECTIVE The aim of this study was to examine the level of myeloperoxidase (MPO) measured before specific treatment in patients presenting to the Emergency Department with acute ischemic stroke and its correlation to mortality and the severity of the stroke. PATIENTS AND METHODS The study was carried out on 55 patients with a confirmed diagnosis of ischemic stroke, and on 44 healthy control ...
Propylthiouracil (PTU) is known to cause vasculitis as a rare complication. We report the case of a patient who developed alveolar haemorrhage and haematuria whilst treated with PTU. The serum was positive for antineutrophil cytoplasmic antibody (ANCA) with myeloperoxidase (MPO) specificity (MPO-ANCA). All symptoms resolved completely after discontinuation of PTU. Alveolar haemorrhage or pulmon...
AIMS Observational studies have suggested a mechanistic link between the leucocyte-derived enzyme myeloperoxidase (MPO) and vasomotor function. Here, we tested whether MPO is systemically affecting vascular tone in humans. METHODS AND RESULTS A total of 12 135 patients were screened for leucocyte peroxidase activity. We identified 15 individuals with low MPO expression and activity (MPO(low))...
The coronavirus disease-19 (COVID-19) pandemic leaded to inevitable expeditious vaccine rollout without sufficient safety profile. Especially, severe acute respiratory syndrome 2 infection has known induce overreacted immune responses such as releasing of proteinase-3 and myeloperoxidase (MPO) by neutrophil. This response leads the concern development autoimmune diseases after COVID-19 vaccinat...
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