although chronic myelogenous leukemia in pregnancy is rare, its management and treatment is more difficult and complicated. treatment of patients with chronic myelogenous leukemia includes bone marrow transplantation, however in less than 30% of patients the donor’s organ would be accepted. to this end, cytotoxic therapy is considered as an alternative therapeutic option. this option provides s...

BackgroundLeukemia is the most common cancer affecting children and remains top cause of death among children.ObjectiveThis study aimed at determining birth outcomes maternal risk factors associated with childhood leukemia in Rwanda.MethodsA case control was conducted Butaro Cancer Referral hospital. The sample 103 cases controls recruited using records for diagnosed Acute lymphocytic (ALL) mye...

Cancer is a major public health problem worldwide. The most important considerable features of cancer cells are uncontrolled proliferation, up-regulated differentiation, and immortality. Crocin, as a bioactive compound of saffron and as a water-soluble carotenoid has radical scavenging, anti-hyperlipidemia, memory improving, and inhibition of tumor growth effects. The present review was designe...

(a) Molecularly-targeted drug treatment in 52 patients Molecular target drug n=52 Underlying malignancy Other drugs* 5(9.6) Malignancy 5 Note.—Numbers of the data are numbers of patients, with percentages in parentheses. emtansine for the treatment of colon cancer, lymphoma, lung cancer, multiple myeloma, and breast cancer, respectively. GIST = gastrointestinal stromal tumor, CML = chronic myel...

abstract: this paper represents a novel use of artificial neural networks in medical science. the proposed technique involves training a multi layer perceptron (mlp) (a kind of artificial neural network) with a bp learning algorithm to recognize a pattern for the diagnosing and prediction of five blood disorders, through the results of blood tests from h1 machine. the blood test parameters and ...

Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells. This process sometimes exhibits abnormalities in blood cells production, causing the so-called dynamical hematological diseases. A severe hematological disease is Chronic Myelogenous Leukemia (CML), a cancer of white blood cells. In some cases...

In present study novel series of benzothiazole derivatives were synthesized and their anti cancer efficacy was analyzed using cancer cell lines (Human Chronic Myelogenous Leukemia). The compounds were synthesized by simple and facile procedures and characterized by IR, H-NMR and Mass spectra study. The synthesized compounds were screened for anti cancer activity using in vitro assays. The compo...

Chloroma, or granulocytic sarcoma, is a rare extramedullary solid hematologic cancer, found concomitant with acute myeloid leukemia. It is infrequently associated with other myeloproliferative disorders or chronic myelogenous leukemia. Chloroma of the testis after allogeneic bone marrow transplantation is particularly sparsely represented in the literature. It is suggested that an appropriate p...

Tumor propagation by cancer stem cells (CSCs) requires their ability to self-renew, and yet the signal pathways involved in this process remain poorly defined. In the December issue of Cancer Cell, Zhao et al. (2007) provide compelling evidence that Wnt/beta-catenin signaling is crucial for the maintenance of chronic myelogenous leukemia (CML) stem cells.