Methoxetamine (MXE) is a psychoactive substance distributed mostly via the Internet and is not liable to legal regulation in Poland. MXE has a toxicity profile similar to that of ketamine but longer-lasting effects. The paper describes a case of acute poisoning that resulted from recreational use of MXE and amphetamine and ended in death. In mid-July 2012, a 31-year old man was admitted to the ...

A method for routine preparation of a solution of 133 Xe gas in saline from commercially available m Xe gas ampoules is described and evaluated. At room temperature and atmospheric pressure, about 25% of the mxe gas dissolves in saline. Xenon-133 binds to the syringe wall or may escape into the air when stored in sealed plastic syringes. Preparation immediately prior to use, short-term storage ...

Methoxetamine (MXE), a ketamine analogue, is one of the new "legal highs" sold on the Internet. The aim of this qualitative study was to provide an initial understanding of what characterizes the experiences induced by MXE. Anonymously written reports (33 persons) on the effects of MXE were collected from public Internet forums and analyzed using the Empirical Phenomenological Psychological Met...

This paper summarizes the results of a series of performance tests carried out as part of an evaluation of diierent graphics workstations. The graphics performance was determined by Viewperf 5.1. In addition, we present some results of a relatively simple graphics benchmark, which measures the raw performance with regard to Gouraud-shading. In order to get a good estimation of the processing po...

Recombinant expression systems have become powerful tools for understanding the structure and function of proteins, including the apolipoproteins that comprise human HDL. However, human apolipoprotein (apo)A-II has proven difficult to produce by recombinant techniques, likely contributing to our lack of knowledge about its structure, specific biological function, and role in cardiovascular dise...

Intein-mediated expressed protein ligation (EPL) permits the site-specific chemical customization of proteins. While traditional techniques have used purified, soluble proteins, we have extended these methods to release and modify intein fusion proteins expressed on the yeast surface, thereby eliminating the need for soluble protein expression and purification. To this end, we sought to simulta...

objective(s): we investigated the contribution of gyra and parc mutational mechanism in decreased ciprofloxacin susceptibility of acinetobacter baumannii isolated from burn wound infections. materials and methods: ciprofloxacin susceptibility of 50 a. baumannii isolates was evaluated by disk diffusion and agar dilution methods. pcr and sequencing were performed for detection of mutation in gyra...

background and objective: use of elastin-like proteins (elps) provides high-performance protein purification without need for chromatography. in line with cost reduction and facilitation of recombinant proteins purification, which represent a high percentage of production costs, in this project, we eliminated the need for proteases in the process of separation of recombinant proteins from elp b...

Mutually exclusive splicing is an important mechanism in a wide range of eukaryotic branches to expand proteome diversity, but the extent of its distribution within a single species and its evolutionary conservation is unknown. Here we present a genome-wide analysis of mutually exclusive spliced exons (MXEs) in Drosophila melanogaster at unprecedented depth. Most of the new MXE candidates are s...