abstract objective autosomal recessive spinal muscular atrophy (sma) is, after cystic fibrosis, the second most common fatal monogenic disorder and the second most common hereditary neuromuscular disease after duchenne dystrophy. the disease is characterized by degeneration of anterior horn cells leading to progressive paralysis with muscular atrophy. depending on the clinical type (werdnig- ho...

duchenne muscular dystrophy (dmd) and the milder allelic becker muscular dystrophy (bmd) are x-linked disorders. both dmd & bmd result from heterogenous mutation in the dystrophin gene and in about 65% of the cases one or more exons of the gene are deleted or duplicated. one third of cases arise from new mutation and the rest are familial. to analyze the prevalence of deletion in iranian patien...

the purpose of the study was to compare physical fitness components of school boys and to develop national norms on speed, endurance, agility and muscular power variables by caft instrument. 12960 students (age groups 7-18) were randomly selected from north, south, east, west and central parts of the country and were compared based on the research variables and the national norms. anova and pos...

background and objective: becker muscular dystrophy (bmd) is a subtype of dystrophinopathies and designated as “mild form of dystrophinopathy”. the frequency rate of the disease is 1:18000 to 1:30000 in different populations and the symptoms are presented at about 8-9 years of age. the diagnostic panel composed of serum ceratin kinase (sck) measurement, electromyography (emg), and as a major co...

l-tyrosine, b6 and folic acid are involved in biosynthesis of dopa and consequently dopamine. the aim of this study was to investigate the antiparkinsonian effect of these agents in perphenazine-induced catatonia in rats. murprogo method or scored muscular rigidity, which is induced by a phenothiazine, was used to evaluate the antiparkinsonian effect of these agents. a significant decrease in m...

spinal muscular atrophies (smas) represent a rare group of inherited disorders that cause progressive degeneration of the anterior horn cells of the spinal cord. the exact cause of the degeneration is unknown. loss of these cells results in a progressive lower motor neuron disease that has no sensory involvement and that is manifested as hypotonia, weakness, and progressive paralysis. kugelberg...

L-tyrosine, B6 and folic acid are involved in biosynthesis of DOPA and consequently dopamine. The aim of this study was to investigate the antiparkinsonian effect of these agents in perphenazine-induced catatonia in rats. Murprogo method or scored muscular rigidity, which is induced by a phenothiazine, was used to evaluate the antiparkinsonian effect of these agents. A significant decrease in m...

how to cite this article: nilipor y, shariatmadari f, abdollah gorji f, rouzrokh m, ghofrani m, karimzadeh p, taghdiri mm,  delavarkasmaei h, ahmadabadi f, bakhshandeh bali mk, nemati h, saket s, jafari n, yaghini o, tonekaboni sh.  evaluation of one hundred pediatric muscle biopsies during a 2-year period in mofid children and toos hospitals. iran j child neurol. 2013 spring;7(2):17-21.   obje...