large unilamellar liposomes and multilamellar vesicles consisting of dmpc interacted with cationic phosphorus-containing dendrimers cpds g3 and g4. dsc and ζ -potential measurements have shown that liposomal-dendrimeric molecular recognition occurs due to the interaction between the complementary surface groups. calorimetric studies indicate that the enthalpy of the transition of the lipids tha...

Large unilamellar liposomes and multilamellar vesicles consisting of DMPC interacted with cationic phosphorus-containing dendrimers CPDs G3 and G4. DSC and ζ -potential measurements have shown that liposomal-dendrimeric molecular recognition occurs due to the interaction between the complementary surface groups. Calorimetric studies indicate that the enthalpy of the transition of the lipids tha...

The organ distribution and half-life in blood of liposome-entrapped [14C]sucrose was examined in rats for two compositions of liposomes having widely differing drug release properties as determined by an in vitro assay in the presence of serum at 37 degrees C. The liposomes were composed of 1) egg phosphatidylcholine-cholesterol, 2:1 molar ratio and of 2) bovine brain sphingomyelin-phosphatidyl...

Liposomes, due to their various forms, require further exploration. These structures can deliver both hydrophilic and hydrophobic drugs for cancer, antibacterial, antifungal, immunomodulation, diagnostics, ophtalmica, vaccines, enzymes and genetic elements. Preparation of liposomes results in different properties for these systems. In addition, based on preparation methods, liposomes types can ...

A simple experimental system was developed for studying the movement of long-chain fatty acids between multilamellar liposomes and soluble proteins capable of binding fatty acids. Oleic acid was incorporated into multilamellar liposomes containing cholesterol and egg yolk lecithin and incubated with albumin or hepatic fatty acid-binding protein. It was found that the fatty acid transferred from...

Intranasal route is one of the most attractive routes for distributing drugs to systemic circulation. Liposomes are used as biocompatible carriers to improve delivery properties across nasal mucosa. The objective of the present study was to formulate acyclovir liposomes and partition into poly-N-vinyl-2-pyrrolidone. Entrapment efficiency showed that multilamellar and unilamellar liposomes were ...

Visceral leishmaniasis (VL) is a chronic debilitating disease prevalent in tropical and subtropical regions, caused by protozoan parasites of the genus Leishmania. Annually, it approximated occurrence 0.2 to 0.4 million novel cases worldwide. The cast film method was used prepared cationic mannosylated liposomes. surface Amphotericin B (Amp B)-bearing multilamellar liposomes covalently coupled ...

Multilamellar liposomes consisting of dipalmitoyl phosphatidylcholine (DPPC) and dicetyl phosphate (DCP) in a molar ratio of 8:2 (DPPC:DCP = 8:2) were coated with three different types of polymers: chitosan, polyvinyl alcohol having a long alkyl chain, and poly(acrylic acid) bearing cholesterols. The existence of polymer layers on the liposome surface was confirmed by measuring the zeta potenti...

As a prerequisite for the use of liposomes for delivery of biologically active agents, techniques are required for the efficient and rapid entrapment of such agents in liposomes. Here we review the variety of procedures available for trapping hydrophilic and hydrophobic compounds. Considerations which are addressed include factors influencing the choice of a particular liposomal system and tech...