background: reduced susceptibility of clostridium difficile to antibiotics is problematic in clinical settings. there is new evidence indicating the cotransfer of toxin-encoding genes and conjugative transposons encoding resistance to antibiotics among different c. difficile strains. to analyze this association, in the current study, we evaluated the frequency of toxigenic c. difficile among th...

background nasal carriage of staphylococcus aureus is a substantial source of human infections. detection and treatment of nasal carriage in children with methicillin-resistant and multidrug resistant s. aureus (mrsa and mdrsa, respectively) may be an important modality in prevention of infections. objectives this study determined the prevalence, antibiotic resistance patterns and risk factors ...

conclusions high mdr isolates of e. coli were observed in this study. the significant association between class 1 integrons and resistance to ciprofloxacin, nalidixic acid, co-trimoxazole, amoxicillin, ceftazidime and tetracycline showed that class 1 integrons have an important role in resistance to these antibiotics in this region. results the highest rate of resistance was observed toward cep...

the emergence of multidrug resistant strains of escherichia coli has complicated treatment decision and may lead to treatment failures. from april to november 2001 we prospectively evaluated the prevalence of resistance to trimethoprim-sulfamethoxazole (sxt), gentamicin, cephalothin, ciprofloxacin, and nitrofurantoin in 220 escherichia coli isolates from patients with urinary tract infections i...

background: tuberculosis (tb) is a major worldwide public health problem. the incidence of tuberculosis has decreased in iran in recent years. however, despite this dramatic decline, tuberculosis is still considered to be a major health problem in iran. objectives: the aim of this study was to investigate the epidemiological situation and main characteristics of tuberculosis in iran. patients a...

background: lower respiratory tract infections are among important causes of morbidity and mortality for all age groups. the emergence of multidrug resistant gram-negative bacilli is an issue of increasing concern. materials and methods: a retrospective study including respiratory specimens (sputum and bal) was conducted in our tertiary care centre. samples were processed for microscopy, cultur...

background and objectives: strains of shigella spp. can cause shigellosis, or bacillary dysentery.that is a public health problem worldwide. the aim of this study was to describe the population structure and genetic relatedness of multidrug resistant s. sonnei and s. flexneri isolated during a one year period from children with diarrhea in tehran, iran. materials and methods: a total of 70 shig...

background and objective:acinetobacter spp.a gram-negative coccobacillus is increasingly reported as important cause of nosocomial infections. multi-drug resistance (mdr) ofacinetobacterspp., raises concerns over our ability to treat serious infections with these organisms. the aim of this study was to determine the frequency and associated risk factors for infections with mdr acinetobacter spp...