The mucus layer continuously covering the gastric mucosa consists of a loosely adherent layer that can be easily removed by suction, leaving a firmly adherent mucus layer attached to the epithelium. These two layers exhibit different gastroprotective roles; therefore, individual regulation of thickness and mucin composition were studied. Mucus thickness was measured in vivo with micropipettes i...

The distribution of basophiloid cells in nasal mucosa was examined both in the patients of nasal allergy and normal controls . Basophiloid cells were stained in alcian blue (P .H. 5.8) with 0.4M MgCl2. 1 ) The basophiloid cells in the nasal mucosa of allergic patients were far outnumbered those of normal controls. 2) The basophiloid cells in the epithelial layer were very few in normal controls...

This paper describes the preparation of new bilayered device comprising a drug containing mucoadhesive layer and a drug free backing layer. Bilaminated films were produced by a casting/ solvent evaporation technique. The mucoadhesive layer was composed of mixture of drug and sodium alginate with or without carbopol 934 P, and backing layer was made of ethyl cellulose. The double layer structure...

mucosa-adhesive gels can be used as a useful mean of delivering drugs to or via mucosal membranes, and in particular buccal mucosa. carbomers are among the best mucosa-adhesive materials known. the aim of this study was to compare the results obtained from the mucosa-adhesive strength of aqueous gels containing carbomers, either alone or in combination, to the data obtained from assessing the d...

Background: The northern pike Esox lucius is a fresh water species belonging to the Esocidae family. It is a carnivorous fish which mostly feeds on invertebrates and fishes. The morphology of its intestine is very useful for understanding the fish’s digestive physiology, diagnosing some intestinal diseases and formulating suitable feeds. OBJECTIVES: This study was designed to determine the anat...

BACKGROUND AND AIMS The early responses of the oesophageal mucosa to acid perfusion may predict subsequent pathology. Mucosal responses to luminal acid may result either from acid permeating through the mucosa or from other unknown transduction mechanisms. In order to better understand the dynamics of acid permeation into the oesophageal mucosa, we measured interstitial pH (pH(int)) of the oeso...

Background and aims: The early responses of the oesophageal mucosa to acid perfusion may predict subsequent pathology. Mucosal responses to luminal acid may result either from acid permeating through the mucosa or from other unknown transduction mechanisms. In order to better understand the dynamics of acid permeation into the oesophageal mucosa, we measured interstitial pH (pHint) of the oesop...

BACKGROUND AND PURPOSE Melatonin is involved in the regulation of colonic motility, and sensation, but little is known about the influence of melatonin on 5-hydroxytryptamine (5-HT) release from colonic mucosa. A tachykinin NK₂ receptor-selective agonist, [β-Ala⁸]-neurokinin A(4-10) [βAla-NKA-(4-10)] can induce 5-HT release from guinea pig colonic mucosa via NK₂ receptors on the mucosal layer. ...

AIM To analyze the risk factors for pancreatic fistula after pancreaticoduodenectomy. METHODS We conducted a retrospective analysis of 539 successive cases of pancreaticoduodenectomy performed at our hospital from March 2012 to October 2015. Pancreatic fistula was diagnosed in strict accordance with the definition of pancreatic fistula from the International Study Group on Pancreatic Fistula....

Background & Aims: Leukoplakia is the most common premalignant or potentially malignant lesion of the oral mucosa and its potentiality for malignant transformation is unpredictable. The aim of the present study was to evaluate p53 expression in normal oral epithelium, leukoplakia and oral squamous cell carcinoma. Methods: The standard Biotin streptavaidin peroxidase immunohistochemical staining...