introduction: the aim of this study was to compare the microleakage of beneath the orthodontic brackets bonded with 3 different bonding techniques and evaluate the effect of thermocycling. methods: one hundred and twenty premolars were randomly divided into 6 groups, received the following treatment: group 1: 37% phosphoric acid gel+unite primer+unite adhesive, group 2: 37% phosphoric acid gel+...

Topical administration of clotrimazole represents the common use therapy in the antimycotic genitourinary tract treatment. Due to the fast self-cleaning action of the vagina, commercially available vaginal dosage forms with clotrimazole cannot assure prolonged contact time with mucosa, therefore the main objective of this study was to develop a dosage form for vaginal administration of clotrima...

AIM To evaluate corneal injury during general anesthesia and analyze the protective effect of medical hydro-gel eye patch in clinics. METHODS Seventy-six patients with 152 eyes undergoing general anesthesia were included. None had positive corneal fluorescein staining before surgery. Both eyes of each patient were analyzed, with one randomly allocated to receive medical hydro-gel eye patch, a...

Introduction: Adhesive dentistry faces complex clinical situations, which require the dentist to be able choose best adhesive protocol offered by universal adhesives. Objective: To present current information about performance in bond strength according etching technique used adhesives, evaluating total technique, selective enamel etching, self-etch and bonding special situations. Methodology: ...

BACKGROUND AND AIMS Oral mucosa and interproximal spaces of the teeth could favor the colonization of periodontopathogenic bacteria, which could be targeted by chemical antiplaque agents such as chlorhexidine, present in different oral hygiene products, thus improving the control of biofilm growth and delaying microbial accumulation. The study aimed to evaluate whether the use of a hydrophobic ...

The aim of this pilot study was to evaluate the effect different vehicles oral hygiene containing green tea and hyaluronic acid on peri-implant clinical parameters. In study, 21 patients with a total 112 implants used one tested: 1) dentifrice (10); 2) Gel (11). who received gel or presented partial fixed rehabilitation supported by implants. Patients were submitted analysis at baseline after 1...

Common adhesives stick to a wide range of materials immediately after they are applied to the surfaces. To prevent indiscriminate sticking, smart adhesive materials that adhere to a specific target surface only under particular conditions are desired. Here we report a polymer hydrogel modified with both β-cyclodextrin (βCD) and 2,2'-bipyridyl (bpy) moieties (βCD-bpy gel) as a functional adhesiv...

Three-dimensional gel matrices provide specialized microenvironments that mimic native tissues and enable stem cells to grow and differentiate into specific cell types. Here, we show that collagen three-dimensional gel matrices prepared in combination with adhesive proteins, such as fibronectin (FN) and laminin (LN), provide significant cues to the differentiation into neuronal lineage of mesen...

The present study is aimed at formulation of alginate (ALG) microspheres with ranitidine (RNT) by the spray drying method. Obtained microspheres were characterized for particle size, surface morphology, entrapment efficiency, drug loading, in vitro drug release and zeta potential. Mucoadhesive properties were examined by a texture analyser and three types of adhesive layers--gelatine discs, muc...