Abstract Introduction: Myofibroblasts are the main stromal components that constitute the desmoplastic reaction of host cells to inductive stimuli exerted by tumor cells. The purpose of this study was to evaluate the score of myofibroblasts using α -smooth muscle actin marker (α–SMA) in mucoepidermoid carcinoma (MEC) in comparison with pleomorphic adenoma (PA)and study the amount presence of t...

Introduction: Mucoepidermoid carcinoma represents one of the most common malignant salivary gland tumors.However, the sclerosing morphologic variant is extremely rare with only 23 reported cases in the English-language literature since it was discovered in 1987. Case Report: Herein, we describe another case that was diagnosed in a 25-year-old woman presenting with a posterior auricular mass, ...

Adenosquamous carcinoma is a rare distinct clinicopathological entity characterized histopathologically by components of both squamous cell carcinoma and adenocarcinoma [1]. This type of carcinoma is described in a variety of sites, including lung, pancreas, and uterine cervix, while the head and neck region is a relatively rare origin for this type of tumor [1]. The existence of adenosquamous ...

introduction: mucoepidermoid carcinoma represents one of the most common malignant salivary gland tumors.however, the sclerosing morphologic variant is extremely rare with only 23 reported cases in the english-language literature since it was discovered in 1987. case report: herein, we describe another case that was diagnosed in a 25-year-old woman presenting with a posterior auricular mass, as...

Recurrent invasive high-grade mucoepidermoid carcinoma of the larynx and hypopharynx is a rare occurrence. These tumors have been commonly associated with salivary gland tumors, most commonly the parotid gland. The patient usually presents with the following symptoms: hoarseness (if larynx is involved), or changes in voice character, sore throat, cough, odynophagia, dysphagia, otalgia, difficul...

mucoepidermoid carcinoma of the pancreas is rare. here, a 63-year-old woman with left upper abdominal pain and abdominal distension is presented. her mucoepidermoid carcinoma was located at the left upper abdomen, arising from the pancreatic body and tail without invasion of pancreatic capsule. on pathologic examination, the tumor consisted of three types of cells, the majority being poorly dif...

introduction the application of immunohistochemical method has resulted in marked improvement of the microscopic diagnosis of neoplasms combined with h&e; staining. although unique cellular antigens have not been found in salivary gland neoplasms, multiple less specific immunomarkers have been used and may be helpful in elucidating the role of myoepithelial differentiation in those neoplasms. t...

BACKGROUND Mucoepidermoid carcinoma arises from major or minor salivary glands, making up 10% of salivary gland tumors. Intraosseous mucoepidermoid carcinomas are rare, and make up only 2% to 3% of all mucoepidermoid carcinomas. The t(11;19) and its CRTC1-MAML2 fusion gene transcript have been identified in mucoepidermoid carcinoma and are associated with a subset of mucoepidermoid carcinomas. ...