Our interest in analyzing peptides and proteins arises from the need, during preclinical and clinical studies, to quantify levels of protein and peptide drugs and their metabolites (the process of bioanalysis). To support the predicted increase in peptides and proteins undergoing such studies, we expect that the demand for immunological and LC-MS/MS bioanalytical methods to increase. We have be...

Comparative analyses utilizing collision induced dissociation (CID) and vacuum ultraviolet photodissociation (VUVPD) for seven isobaric disaccharides have been performed in order to differentiate the linkage type and anomeric configuration of the isomers. Although an individual CID spectrum of a disaccharide ion provides information related to its structure, CID does not sufficiently differenti...

PURPOSE This study aims to propose a metabolic syndrome (MS) biological age model, through which overall evaluation and management of the health status and aging state in MS can be done easily. Through this model, we hope to provide a novel evaluation and management health index that can be utilized in various health care fields. PATIENT AND METHODS MS parameters from American Heart Associati...

in this study, 120 aegilops crassa (mmdd genome) accessions from iran were evaluated for high molecular weight proteins. based on sds-page analysis, 17 bands were selected and mass spectrometry was used for protein identification. among 17 bands selected for maldi-tof-tof-ms analyzing, only 4 bands were identified as high molecular weight glutenin subunit similar to aegilops ventricosa and trit...

De novo sequencing of tandem (MS/MS) mass spectra represents the only way to determine the sequence of proteins from organisms with unknown genomes, or the ones not directly inscribed in a genome-such as antibodies, or novel splice variants. Top-down mass spectrometry provides new opportunities for analyzing such proteins; however, retrieving a complete protein sequence from top-down MS/MS spec...

this paper proposes an optimal transmission expansion planning (tep) which is based on determining share of each line in merchandizing surplus (ms) of system, determining by independent system operator (iso). the more share of a line in ms of system denotes the priority of a line for expansion. the procedure of determining ms of each line in a power system is based on determining the ms share o...