نتایج جستجو برای: mrna gene expression
تعداد نتایج: 1641040 فیلتر نتایج به سال:
Background: Vaccines have played a special role in controlling and reducing mortality from infectious diseases. In this regard, DNA vaccines were developed to ease the production and reduce the risks of traditional vaccines. Human papillomavirus (HPV) has been introduced as the causing agent of cervical cancer. The capsid protein (L1) of HPV has been used to produce subunit and DNA vaccines. Th...
Context:MicroRNAs (miRNAs) are a class of short, endogenously-initiated, non-coding RNAs that post-transcriptionally control gene expression via translational repression or mRNA turnover. MiRNAs have attracted much attention in recent years as they play critical roles in gene expression and are promising tools with many biotech and therapeutic applications. The molecular mechanisms und...
conclusions further studies on the role of hepcidin in pathogenesis of chc are needed to assess the potency of its use in antiviral treatment. results patients with chc had lower hepcidin mrna expression and more frequently iron deposits in hepatocytes than subjects with chb did. in chc group, hepcidin mrna expression was positively correlated with alanine aminotransferase activity and serum ir...
hydrogen sulfide (h2s) has been shown to protect the gastric mucosa through several protective mechanisms but till now its effect on mrna expression of sodium bicarbonate cotransporter 1 (nbc1), trefoil factor1 (tff1) and trefoil factor2 (tff2) was not investigated. this study was aimed to evaluate the effect of h2s on mrna expression of nbc1, tff1 and tff2 in rat gastric mucosa in response to ...
(SCNT) embryos of buffaloes. 2. To study gene expression profile of important developmental genes at different stages of SCNT cloned embryo. 3. To study epigenetic reprogramming during early developments of SCNT embryos Materials and Methods: Expression analysis of developmental genes was done in different (ovarian granulose and cumulus and skin fibroblasts) donor cells; in vitro maturing oocyt...
Background: The aim of this research was to determine the Mn superoxide dismutase (Mn SOD) gene expression and the impact of oxidant and inflammatory markers on Mn SOD gene expression in active men and women. Methods: This research was a semi-experimental with repetitious measurement, and 24 active men (12) and women (12) (21-23 years) voluntarily participated in this research after ...
Background & Aims: KAI1 is a tumor suppressor gene and inhibitor of metastasis in a wide range of malignancies. While it is ubiquitously expressed in normal tissues, KAI1 expression is down regulated in tumors. The present research proposal aims semi quantitative evaluation of KAI1 mRNA expression in Iranian patients with Squamous Cell Carcinoma of Esophagus(SCCE) on finding a correlation betw...
background: leptin and adiponectin are the two key metabolic hormones secreted from adipocytes to control food intake and energy expenditure. the action of both hormones in regulation of gonadotropin releasing hormone (gnrh) secretion from the hypothalamus is mediated through kisspeptins. kisspeptins are products of kiss-1 gene. leptin and adiponectin are modulators of kiss-1 expression in the ...
Background: The purpose of this study was to investigate the effect of concurrent training on pre-inflammatory (IL-1β, TNF-α) and anti-inflammatory (IL-10) cytokines gene expression in women with type2 diabetes. Methods: 18-patients (age30-38, >130 glycemic index) were selected, randomly, and divided into control (n=6) the concurrent training(diabetes, n=6) and the concurrent training (healthy...
Background: RNA interference (RNAi) is the mechanism of gene silencing-mediated messenger RNA degradation by small interference RNA (siRNA), which becomes a powerful tool for in vivo research, especially in the areas of cancer. In this research, the potential use of an expression vector as a specific siRNA producing tool for silencing of Bcr-abl in K562 cell line has been investigated. Methods:...
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