The evolution of industrial "rms has recently passed from a strong growth phase to a phase where there is a greater complexi"cation of products: widening the range of products in catalogues, diversi"cation and personalization of models. The current trend is to use, with production management techniques such as classical manufacturing resource planning (MRP2), the concept of two level master pro...

Recently, many novel paradigms, concepts and technologies, which lay the foundation for new revolution in manufacturing environments, have emerged make it faster to address critical decisions today supply chain 4.0 (SC4.0), with flexibility, resilience, sustainability quality criteria. The current power of computational resources enables intelligent optimisation algorithms process data such a w...

The purpose of this article is to propose a guide for the digital transformation (4.0) manufacturing SME’s medium-term production planning process, master schedule (MPS). A model current MPS process group SMEs presented as starting point toward digitization. state reveals lack tools support decision making and need increase reliability input data make more agile. Industry 4.0 technologies model...

Risks arising from the effect of disruptions and unsustainable practices constantly push supply chain to uncompetitive positions. A smart production planning control process must successfully address both risks by reducing them, thereby strengthening (SC) resilience its ability survive in long term. On one hand, antidisruptive potential inherent sustainability implications zero-defect manufactu...

this article reviews will focus on the concept and formation of micro particles (mps) in circulation and their role in transfusion medicine and immune system. mps are cell membrane derived vesicles which express markers of their parent cells and are found in circulation at low levels. exact functions of mps are unclear. in here, physiological almost all types of circulating mps including platel...

Simulation is useful for the evaluation of a Master Production/distribution Schedule (MPS). Also, the goal of this paper is the study of the design of a simulation model by reducing its complexity. According to theory of constraints, we want to build reduced models composed exclusively by bottlenecks and a neural network. Particularly a multilayer perceptron, is used. The structure of the netwo...

background: activated platelets shed microparticles (mps) in vivo and certainly in vitro under storage. like platelets, platelet-derived mps contribute to hemostatic and inflammatory responses. we sought to determine the interactions between platelet mps and peripheral b lymphocytes in the healthy blood circulation to propose a possible role for platelet mps in the functioning of b cells.   mat...

this article reviews will focus on the concept and formation of micro particles (mps) in circulation and their role in transfusion medicine and immune system. mps are cell membrane derived vesicles which express markers of their parent cells and are found in circulation at low levels. exact functions of mps are unclear. in here, physiological almost all types of circulating mps including platel...

task graph scheduling is a multi-objective optimization and np-hard problem. in this paper a new algorithm on homogeneous multiprocessors systems is proposed. basically, scheduling algorithms are targeted to balance the two parameters of time and energy consumption. these two parameters are up to a certain limit in contrast with each other and improvement of one causes reduction in the other on...

Background: Microparticles (MPs) are small vesicles released from the cell membrane. Accordingly, these contain active molecules to mediate biological processes, including cell proliferation and cell cycle progression. The fusion of myeloma cell lines with immunized B lymphocytes is a critical step of hybridoma technology. MPs modulate lymphoproliferation, thereby facilitating B cell expansion ...