By adapting a novel surfactant exchange method, in which surfactants inside mesopores are completely exchanged by surfactants with longer alkyl chain lengths, pore-expansion of monodisperse mesoporous silica spheres (MMSS) with radially ordered hexagonal regularity was attained while retaining spherical morphology and high monodispersity.

Monodisperse lipid-coated microbubbles are a promising route to unlock the full potential of ultrasound contrast agents for medical diagnosis and therapy. Here, we present stand-alone lab-on-a-chip instrument that allows be formed with high monodispersity at production rates. Key maintaining long-term stable, controlled, safe operation microfluidic device control over output size distribution i...

A novel fluorescent nanoparticle was prepared via a simple self-assembly technique based on water-soluble conjugated polymers (CPs) and Ag@SiO(2) core-shell nanoparticles. Core-shell nanoparticles with silver NPs core show a unique property referred to as metal-enhanced fluorescence (MEF). In the present work, the cationic conjugated polymer poly[9,9'-bis(6''-(N,N,N-trimethylammonium)-hexyl) fl...

BACKGROUND Cre recombinase is a common reagent used for the in vivo on/off switching of the expression of target genes flanked by loxP sites. In particular, recombinant TAT-Cre fusion constructs purified from bacteria have been used to promote the cell uptake of the enzyme. However, the recovery of active TAT-Cre remains a demanding process and its specific activity varies significantly among b...

The synthesis and magnetic properties of Ni nanoparticles containing <150 atoms are described. These materials are prepared in an organic solvent using hydrophobic dendrimers as templates, which results in a high degree of size monodispersity. The dendrimer-encapsulated nanoparticles were characterized by UV-vis spectroscopy, transmission electron microscopy, and energy dispersive spectroscopy....

Here we report a droplet microfluidic method to prepare a novel type of polymeric microbeads with monodispersity and macroporosity, and investigate their application as immunological biosensors for the detection of biological species. The matrix of such microbeads is based on macroporous monolithic textures configured with tailored pores ranging from hundreds of nanometers to a few microns with...