Integrating Dock-Door Assignment and Vehicle Routing in Cross-Docking

The vehicle routing problem with cross-docking (VRPCD) consists in defining a set of routes that satisfy transportation requests between a set of pickup points and a set of delivery points. The vehicles bring goods from pickup locations to a cross-docking platform, where the items may be consolidated for efficient delivery. In this paper we propose a new solution methodology for this problem. I...

Introduction: The aim of this study was to assess the effect of Ca2+/calmodulin-dependent kinase IIα (CaMKIIα) inhibitor (KN-93) injection into the locus coeruleus (LC) on the modulation of withdrawal signs. We also sought to study the effect of chronic morphine administration on CaMKIIα activity in the rat LC. Methods: The research was based on behavioral and molecular studies. In the behav...

introduction: the aim of this study was to assess the effect of ca2+/calmodulin-dependent kinase iiα (camkiiα) inhibitor (kn-93) injection into the locus coeruleus (lc) on the modulation of withdrawal signs. we also sought to study the effect of chronic morphine administration on camkiiα activity in the rat lc. methods: the research was based on behavioral and molecular studies. in the behavior...

in addition to increment of the vehicle sprung mass, the main physical effects of addition of cng tank to the vehicle are the longitudinal and height displacement of center of gravity, which have the most influences on the handling, braking, roll stability and spin stability of the vehicle. increment of cng tank mass to the sprung mass of the vehicle increases the vehicle under-steer gradient, ...

Density functional theory (DFT) calculations were performed on tripeptide arginyl-glycyl-aspartic acid (RGD) as an efficient drug carrier to deliver the commercially famous cyclophosphamide (CP) anticancer drug within ethanol solution. The most negative binding energy (-5.22 kcal/mol) was measured for the CP-RGD-7 created through the H-bond interaction between the P=O (phosphoryl) oxygen atom o...

with the aim of reducing cost of electricity consumption and peak load reduction, tools requirement for better managing electricity consumption have become inevitable in recent years. smart home has some equipment which are controllable and this ability is used for increasing comfort and minimizing electricity cost for residence. as a key component of smart home , electric vehicle(ev) ,increase...

nowadays, the use of small vehicles is spreading among urban areas and one sort of these vehicles are three-wheeled vehicles (twvs) which can be competitive with four-wheeled urban vehicles (fwvs) in aspects such as smallness, simple manufacturing, and low tire rolling resistance, fuel consumption and so on. the most critical instability associated with twvs is the roll over. in this paper a ti...