The Galleria mellonella infection model was used to assess the in vivo efficacy of phage therapy against laboratory and clinical strains of Pseudomonas aeruginosa. In a first series of experiments, Galleria were infected with the laboratory strain P. aeruginosa PAO1 and were treated with varying multiplicity of infection (MOI) of phages either 2h post-infection (treatment) or 2h pre-infection (...

As a first step in evaluating the tumor suppressor activity of the manganese superoxide dismutase (MnSOD) gene on established tumors in vivo, we used adenovirus-mediated gene transfer as a means of delivering the MnSOD cDNA to hamster cheek pouch carcinoma (HCPC-1) cells in vitro. HCPC-1 cells were transduced with the adenovirus-MnSOD construct (AdMnSOD) at multiplicities of infectivity (MOI) o...

Helicobacter pylori infection of the human stomach causes chronic gastritis that can lead to gastric cancer. Because activated lymphocytes persist in the gastric mucosa, and because a high multiplicity of infection (MOI) of H. pylori is needed to induce apoptosis in vitro, we speculated that resistance of lymphocytes to apoptosis is an important feature of the immune response to H. pylori. Fres...

A cross-sectional survey was done to assess the missed opportunity for immunization (MOI) in children under two years of age attending Medical Outpatient, Newborn Follow-up Service and Immunization Clinic of Institute of Child Health and to evaluate interventions. Baseline survey phase-I was done and two interventions: (i) education and awareness of immunization among health personnel; and (ii)...

INTRODUCTION TO THE PROBLEM Muhimbili Orthopaedic Institute (MOI) is a public, academic tertiary care referral center in Dar es Salaam, Tanzania, East Africa. MOI is the main referral center for orthopedic and neurosurgical patients in Tanzania. In July 2014, the Radiology Department at MOI consisted of two attending radiologists, 10 technologists, and three IT staff with imaging capabilities o...

A field study was conducted to measure the effect of a bat’s weight and mass moment of inertia (MOI) on the swing speed. The study involved 16 amateur slow-pitch softball players of two skill levels and two groups of bats. One bat group had a constant MOI, but varying weight, while the other group had constant weight, but varying MOI. Players were assigned to either the constant MOI or constant...

The magneto-optic imager (MOI) is a powerful device for the nondestructive inspection (NDI) of aging aircraft. MOI produces analog images of magnetic flux leakage associated with eddy current distribution around surface and subsurface structures. The main advantages of using MOI are its fast inspection speed and easy interpretation compared with conventional Eddy Current NDI instruments. Howeve...

Magneto-Optic Imaging (MOI) is a relatively new nondestructive evaluation modality that provides real time images of surface and subsurface features. In this technique, flux leakage maps associated with applied currents are recorded and monitored to locate material defects. Various factors affect the sensitivity of nondestructive evaluation using MOI including structure geometry, instrumentatio...

A review is presented of the importance of the moment of inertia (MOI) to the performance of a sporting instrument. It is shown that for a given coefficient of restitution (COR), both the intrinsic power and the swing speed of a tennis racquet or baseball bat correlate strongly with the MOI about an axis through the handle and only weakly with the mass. It is further shown that for non-wood bas...

Individuals living in endemic areas generally harbour multiple parasite strains. Multiplicity of infection (MOI) can be an indicator of immune status and transmission intensity. It has a potentially confounding effect on a number of population genetic analyses, which often assume isolates are clonal. Polymerase chain reaction-based approaches to estimate MOI can lack sensitivity. For example, i...