ors. It was not about Moe Bergman, but the name of the musical is a metaphor for Moe. He was an unpretentious mover and shaker who made major contributions in several different areas. He had an amazing ability in addressing a diffi cult problem to demonstrate personality traits that were appropriate for the task at hand. On many occasions, he demonstrated an ability to address several diverse p...

Dette er det 3. intervjuet i tidsskriftets løpende Forskerhjørnet-serie.

Olfaction exerts a profound influence on reproductive physiology and behavior in many animals, including rodents. Odors are recognized by sensory neurons residing in the main olfactory epithelium (MOE) and the vomeronasal organ (VNO) in mice and many other vertebrates. The relative contributions of the MOE and VNO in the display of female behaviors are not well understood. Mice null for Cnga2 o...

Cilia of olfactory sensory neurons are the primary sensory organelles for olfaction. The detection of odorants by the main olfactory epithelium (MOE) depends on coupling of odorant receptors to the type 3 adenylyl cyclase (AC3) in olfactory cilia. We monitored the effect of airflow on electro-olfactogram (EOG) responses and found that the MOE of mice can sense mechanical forces generated by air...

Terrestrial vertebrates have evolved two anatomically and mechanistically distinct chemosensory structures: the main olfactory epithelium (MOE) and the vomeronasal organ (VNO). Although it has been generally thought that pheromones are detected through the VNO, whereas other chemicals are sensed by the MOE, recent evidence suggests that some pheromones may be detected through the MOE. Odorant r...

Laser scanning of fiber angles has shown to be a powerful tool to establish bending MOE profiles along boards. This study aims at investigating the accuracy of the MOE variation determined on basis of fiber angles obtained from laser scanning. Material employed was a board of Norway spruce of dimension 50×150×3900 mm. Firstly fiber angles on four surfaces were identified using a WoodEye scanner...

To achieve a better tracking of time-varying channel parameters, a structure using blind adaptive minimum output energy (MOE) detection in conjunction with a Rake combining diversity for direct-sequence code-division multiple-access (DS/CDMA) communications over the frequency selective multipath fading channels is introduced. In this MOE-RAKE structure, the signal replicas received from multipl...

Mixture-of-experts (MoE) models are a powerful paradigm for modeling of data arising from complex data generating processes (DGPs). In this article, we demonstrate how different MoE models can be constructed to approximate the underlying DGPs of arbitrary types of data. Due to the probabilistic nature of MoE models, we propose the maximum quasilikelihood (MQL) estimator as a method for estimati...

In a companion study published in this issue (p. 83), we showed that chimeric substrates containing 2'-methoxyethyl (MOE) nucleotides inhibited human RNase H1 activity. In this study, we prepared chimeric substrates containing a central DNA region with flanking northern-biased MOE nucleotides hybridized to complementary RNA. Conformationally biased and flexible modified nucleotides were positio...

Type 1 diabetes (T1D), an autoimmune inflammatory disorder, develops as a consequence of pancreatic β-cell destruction and results in hyperglycaemia. Since current T1D therapy mainly involves insulin replacement, the aim of the present study was to evaluate the therapeutic potential of Origanum vulgare L. ssp. hirtum (Greek oregano) leaf extract rich in biophenols for the treatment of T1D. The ...