نتایج جستجو برای: mixed lymphocyte reaction

تعداد نتایج: 677277  

Journal: :Clinical & Experimental Immunology 2008

Akbar Farjadfar Derek Kennedy Gholamhossein Hassanshahi, Hasan Ebrahimi Masoud Soleimani, Mohammad Kazemi Arabadadi Naser Ajmadbeigi

Background: Unrestricted somatic stem cells (USSC) are cord blood stem cells that have been considered as candidates for the regulation of immune responses. Therefore, potential exists for their use in the suppression of immune response after transplantation surgery. Objective: The aim of this study was evaluation of the effect of USSC on mixed lymphocyte reaction (MLR) as a model for graft rej...

Journal: :Bioscience, biotechnology, and biochemistry 2002
Hiroyuki Nagata Hiroshi Yano Kimihito Sasaki Soichiro Sato Satoshi Nakanishi Isami Takahashi Tatsuya Tamaoki

Lck is a Src-family tyrosine kinase that is expressed predominantly in T cells, where it plays important roles in T-cell activation. Lymphostin was isolated from Streptomyces sp. as an inhibitor of Lck. As previously reported, lymphostin inhibited Lck (IC50 0.05 microM) and the mixed lymphocyte reaction (IC50 0.009 microM). We have now examined the mechanism of inhibition by lymphostin. Lymphos...

Journal: :The Journal of Experimental Medicine 1976
M M Kuntz J B Innes M E Weksler

An autologous mixed lymphocyte reaction was demonstrated between T and non-T lymphocytes. Sheep erythrocyte rosetting was used to separate human lymphocytes into T and non-T lymphoid preparations. Non-T lymphocytes stimulated the proliferation of autologous T lymphocytes. The cell in this preparation that was most stimulatory had the characteristics of a K lymphocyte. The allogeneic mixed lymph...

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