نتایج جستجو برای: mitochondria reactive oxygen species

تعداد نتایج: 832736  

Journal: :Journal of Biological Chemistry 2003

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Journal: :Circulation Research 2014

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Journal: :the iranian journal of pharmaceutical research 0
fatemeh shaki 1- faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran. 2- faculty of pharmacy, manzandaran university of medical sciences, sari, iran. 3- students research committee, school of pharmacy shahid beheshti university of medical sciences, tehran, iran. jalal pourahmad 1- faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran. 2- pharmaceutical sciences research center, shahid beheshti university of medical sciences, tehran, iran.

considerable evidence suggests that mitochondrial dysfunction contributes to the toxicity of uranyl acetate (ua), a soluble salt of depleted uranium (du). we examined the ability of the two antioxidants, beta-glucan and butylated hydroxyl toluene (bht), to prevent ua-induced mitochondrial dysfunction using rat-isolated kidney mitochondria. beta-glucan (150 nm) and bht (20 nm) attenuated ua-indu...

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ژورنال: مجله دانشگاه علوم پزشکی مازندران 2015
خوش طبیعت , لعیا , مهدوی, مجید ,

Abstract During normal cellular activities Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) are produced. In addition to beneficial functions they play a critical role in cell death and prevent apoptosis. Every cell is equipped with an extensive antioxidant defense system to combat the excessive production of active radicals. Oxidative stress occurs with destruction of cellu...

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Journal: :iranian journal of allergy, asthma and immunology 0
monireh mohsenzadegan department of immunology, school of public health, tehran university of medical sciences, tehran, iran. abbas mirshafiey department of immunology, school of public health, tehran university of medical sciences, tehran, iran

reactive oxygen species (ros) are produced in many normal and abnormal processes in humans, including atheroma, asthma, joint diseases, cancer, and aging. basal levels of ros production  in  cells  could  be  related  to  several  physiological functions  including  cell proliferation, apoptosis and homeostasis. however, excessive ros production above basal levels would impair and oxidize dna, ...

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Journal: :the iranian journal of pharmaceutical research 0
mir-jamal hosseini 1- faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran. 2- department of pharmacology and toxicology, school of pharmacy, zanjan university of medical sciences, zanjan, iran. 3- student research committee, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. fatemeh shaki shaki 1- faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran. 2- department of pharmacology and toxicology, school of pharmacy, mazandaran university of medical sciences, sari, iran. mahmoud ghazi-khansari department of pharmacology, school of medicine, tehran university of medical sciences, tehran, iran. jalal pourahmad faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran.

arsenic exposure mainly through food and water has been shown to be associated with increased incidence of numerous cancers and non-cancer harmful health. it is also used in cancer chemotherapy and treatment of several cancer types due to its apoptogenic effects in the various cancer and normal cell lines. we have already reported that liver is the storage site and important target organ in as ...

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Journal: The Iranian Journal of Pharmaceutical Research 2012
Fatemeh Shaki, Jalal Pourahmad,

Considerable evidence suggests that mitochondrial dysfunction contributes to the toxicity of uranyl acetate (UA), a soluble salt of depleted uranium (DU). We examined the ability of the two antioxidants, beta-glucan and butylated hydroxyl toluene (BHT), to prevent UA-induced mitochondrial dysfunction using rat-isolated kidney mitochondria. Beta-glucan (150 nM) and BHT (20 nM) attenuated UA-indu...

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ژورنال: مجله علوم پزشکی رازی 2018
زرین گل, مینا,

    ROS (Reactive Oxygen Species) are small, short-lived and highly reactive molecules that can oxidize proteins, lipids and DNA. ROS are formed by incomplete one-electron reduction of oxygen. ROS include oxygen anions, free radicals, including superoxide and hydroxyl radicals, and peroxides such as hydrogen peroxide (H2O2).  Autophagy is a catabolic pathway for degradation ...

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Journal: Iranian Journal of Pharmaceutical Research 2012
Fatemeh Shaki, Jalal Pourahmad,

Considerable evidence suggests that mitochondrial dysfunction contributes to the toxicity of uranyl acetate (UA), a soluble salt of depleted uranium (DU). We examined the ability of the two antioxidants, beta-glucan and butylated hydroxyl toluene (BHT), to prevent UA-induced mitochondrial dysfunction using rat-isolated kidney mitochondria. Beta-glucan (150 nM) and BHT (20 nM) attenuated UA-indu...

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2017
Ayla Ozcan Metin Ogun

Reactive species or free radicals include reactive oxygen and nitrogen species that are called reactive oxygen nitrogen species. Reactive oxygen species are formed as a natural by-product of the normal metabolism of oxygen and have significant roles in cell signaling and homeostasis. The reactive oxygen species are generated as a byproduct of biochemical reactions, in mitochondria, peroxisomes,...

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