نتایج جستجو برای: mitochondria

تعداد نتایج: 46868  

Journal: :gastroenterology and hepatology from bed to bench 0
pedram azimzadeh reproductive biotechnology research center, avicenna research institute, acecr, tehran, iran hamid asadzadeh aghdaei basic and molecular epidemiology of gastrointestinal disorders, gastroenterology and liver diseases research institute, shahid beheshti university of medical sciences, tehran, iran peyman tarban basic and molecular epidemiology of gastrointestinal disorders, gastroenterology and liver diseases research institute, shahid beheshti university of medical sciences, tehran, iran mohammad mahdi akhondi reproductive biotechnology research center, avicenna research institute, acecr, tehran, iran abolfazl shirazi reproductive biotechnology research center, avicenna research institute, acecr, tehran, iran hamid reza khorram khorshid genetic research center, university of social welfare and rehabilitation sciences, tehran, iran

aim : the aim of this study was to evaluate and compare three available methods for mitochondrial isolation from a human cell line to predict the best method for each probable application.   background : organelle isolation is gaining importance in experimental laboratory settings. mitochondrial dysfunction may affect tumorgenesis process. there are some evidences that transplantation of health...

Journal: :the iranian journal of pharmaceutical research 0
fatemeh shaki 1- faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran. 2- faculty of pharmacy, manzandaran university of medical sciences, sari, iran. 3- students research committee, school of pharmacy shahid beheshti university of medical sciences, tehran, iran. jalal pourahmad 1- faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran. 2- pharmaceutical sciences research center, shahid beheshti university of medical sciences, tehran, iran.

considerable evidence suggests that mitochondrial dysfunction contributes to the toxicity of uranyl acetate (ua), a soluble salt of depleted uranium (du). we examined the ability of the two antioxidants, beta-glucan and butylated hydroxyl toluene (bht), to prevent ua-induced mitochondrial dysfunction using rat-isolated kidney mitochondria. beta-glucan (150 nm) and bht (20 nm) attenuated ua-indu...

Previous studies demonstrated that CSE induces oxidative stress and its consequences on isolated mitochondria obtained from lung, heart and brain which may provide insight into the role of CSE in human health and disease. The present study was carried out to further characterize and compare toxic effect of CSE extract on isolated mitochondria obtained from either a directly contacting tissue (i...

Considerable evidence suggests that mitochondrial dysfunction contributes to the toxicity of uranyl acetate (UA), a soluble salt of depleted uranium (DU). We examined the ability of the two antioxidants, beta-glucan and butylated hydroxyl toluene (BHT), to prevent UA-induced mitochondrial dysfunction using rat-isolated kidney mitochondria. Beta-glucan (150 nM) and BHT (20 nM) attenuated UA-indu...

Journal: :medical journal of islamic republic of iran 0
mh sanati from the national research center for genetic engineering and biotechnology, tehran, i. r. iran pr carnegie the biotechnology research grpup, murdoch university, western australia 6150, australia

when pooled immunoglobulin g (igg) from patients with multiple sclerosis (ms) was used to probe a human fetal spinal cord λgt 11 cdna library, the igg was found to bind to a predicted epitope of human mitochondrial nd4 sequence. to investigate the involvement of the nd4 as an autoantigen in ms, we determined the presence of specific antibody in the serum of ms patients and serum samples of some...

Considerable evidence suggests that mitochondrial dysfunction contributes to the toxicity of uranyl acetate (UA), a soluble salt of depleted uranium (DU). We examined the ability of the two antioxidants, beta-glucan and butylated hydroxyl toluene (BHT), to prevent UA-induced mitochondrial dysfunction using rat-isolated kidney mitochondria. Beta-glucan (150 nM) and BHT (20 nM) attenuated UA-indu...

Journal: :iranian journal of pharmaceutical research 0
akram ranjbar department of toxicology and pharmacology, school of pharmacy, hamadan university of medical sciences, hamadan, iran mohammad sharifzadeh faculty of pharmacy, and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran jamshid karimi department of biochemistry, school of medicine, hamadan university of medical sciences, hamadan, iran. heidar tavilani tavilani department of biochemistry, school of medicine, hamadan university of medical sciences, hamadan, iran maryam baeeri baeeri faculty of pharmacy, and pharmaceutical sciences research center, tehran university of medical sciences, tehran, iran tavakol heidary shayesteh department of toxicology and pharmacology, school of pharmacy, hamadan university of medical sciences, hamadan, iran

anti-oxidant effects of propofol (2, 6-diisopropylphenol) were evaluated agains carbon tetrachloridet ccl4 -induced oxidative stress in rat liver. 30 male rats were equally divided in to 6 groups (5 rats each). group i (control), while group ii was given ccl4 (3 ml /kg/day, ip). animals of groups iii received only propofol (10 mg/kg/day, ip). group iv was given propofol+ ccl4. group v was admin...

Journal: :iranian journal of pharmaceutical research 0
parvaneh naserzadeh department of pharmaceutical sciences, islamic azad university, tehran, iran. mir-jamal hosseini department of pharmacology and toxicology, school of pharmacy, zanjan university of medical sciences, zanjan, iran sepideh arbabi department of pharmaceutical sciences, islamic azad university, tehran, iran. jalal pourahmad -

previous studies demonstrated that cse induces oxidative stress and its consequences on isolated mitochondria obtained from lung, heart and brain which may provide insight into the role of cse in human health and disease. the present study was carried out to further characterize and compare toxic effect of cse extract on isolated mitochondria obtained from either a directly contacting tissue (i...

Journal: :iranian journal of child neurology 0
gholamreza zamani pediatric neurology department, children’s medical center, tehran university of medical sciences, tehran, iran

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شکی, فاطمه, شکرزاده , محمد, علیدوست, فائزه , محمدی , ابراهیم, نوریان , یزدان, واعظی, نرگس,

Background and purpose: Resveratrol (RSV) is a naturally existing polyphenolic compound abundantly found in grapes and several plants. It has potent free radical scavenger and antioxidative properties with significant effects in reducing oxidative damage. Oxidative stress and mitochondrial dysfunction contribute to PQ induced tissue damage. In this study, the protective effect of RSV was invest...

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