The release of object during robotic micromanipulation operations stays a challenge. The adhesion forces have to be known to improve micromanipulation tasks. Adhesion models build from macrophysics (continuum mechanics) or from nanophysics (atomic scale interactions) do not fit well experiments on the microscale. This is due to some phenomenon which are specific to the microphysics. Some of the...

When simulating multiscale stochastic differential equations (SDEs) in high-dimensions, separation of timescales, stochastic noise and high-dimensionality can make simulations prohibitively expensive. The computational cost is dictated by microscale properties and interactions of many variables, while the behavior of interest often occurs at the macroscale level and at large time scales, often ...

PURPOSE This study aimed to develop an anti-inflammation system consisting of epigallo-catechin-3-gallate (EGCG) encapsulated in poly(lactide-co-glycolic acid) (PLGA) particles to promote wound healing. METHODS Nano- and microscale PLGA particles were fabricated using a water/oil/water emulsion solvent evaporation method. The optimal particle size was determined based on drug delivery efficie...

IMPORTANCE OF THE FIELD Pharmacokinetic-pharmacodynamic (PK-PD) modeling enables quantitative prediction of the dose-response relationship. Recent advances in microscale technology enabled researchers to create in vitro systems that mimic biological systems more closely. Combination of mathematical modeling and microscale technology offers the possibility of faster, cheaper and more accurate pr...

Silica (SiO2) nanoparticles are being progressively applied in various applications, including cosmetics, food technology, and medical diagnostics. Although crystalline SiO2 is a known carcinogen, the carcinogenicity of SiO2 nanoparticles remains unclear. Here, we assessed the cytotoxic effects and DNA injury induced by exposure to various dosages of SiO2 nanoparticles at 0-2400 mg/mL (0-3200 m...

Scaling law for direct current field emission-driven microscale gas breakdown" (2012). Articles you may be interested in Generalized criterion for thermo-field emission driven electrical breakdown of gases Appl. Using field emission to control the electron energy distribution in high-pressure microdischarges at microscale dimensions Appl. Physical mechanisms of self-organization and formation o...