نتایج جستجو برای: microrna 370

تعداد نتایج: 44651  

2017
Xin Liu You-Guang Huang Cong-Guo Jin Yong-Chun Zhou Xiao-Qun Chen Jia Li Yan Chen Mei Li Qian Yao Ke Li Min Lan Jia-Gui Ye Xi-Cai Wang

Abnormal microRNA-370 (miR-370) expression has been frequently reported in several types of cancers, including lung cancer. However, the role and molecular mechanisms of miR-370 in regulating the growth and metastasis of lung cancer have not been clarified. Here, we show higher levels of epidermal growth factor receptor (EGFR), but lower levels of miR-370 expression in most human lung cancer ce...

2016
Hongsheng Liu Ning Yang Zhonghua Fei Jie Qiu Dongwen Ma Xinmei Liu Guoqiang Cai Sheng Li

Coronary artery disease (CAD) requires more accurate diagnostic methods, for which circulating microRNAs (miRNAs) are promising non-invasive biomarkers. miR-208a and miR-370 are two key molecules in cardiac hemostasis and lipid metabolism, respectively. The aim of the present study was to evaluate their potency as diagnostic biomarkers for CAD. Plasma miR-208a and miR-370 were quantitated by re...

Journal: :The British journal of nutrition 2014
R O Benatti A M Melo F O Borges L M Ignacio-Souza L A P Simino M Milanski L A Velloso M A Torsoni A S Torsoni

Maternal consumption of a high-fat diet (HFD) during pregnancy and lactation is closely related to hepatic lipid accumulation, insulin resistance and increased serum cytokine levels in offspring and into their adulthood. MicroRNA (miRNA) have been implicated in cholesterol biosynthesis and fatty acid metabolism. We evaluated the modulation of hepatic fatty acid synthesis (de novo), β-oxidation ...

2013
Gerald W. Dorn, II

MicroRNAs are nature’s dimmer switches for protein translation. When expressed in sufficient abundance, these singlestranded small RNAs bind to complementary nucleotide sequences in the 3' untranslated regions of target mRNAs and direct them to RNA-induced silencing complexes (RISCs) for translational suppression and degradation. Although much has been learned about the molecular mechanisms of ...

2015
Grzegorz Stachowiak Agnieszka Zając Marek Nowak Tomasz Stetkiewicz Jacek R. Wilczyński

Adverse changes in hemostasis of menopausal women, observed e.g. in atherosclerotic or neoplastic cases, are of multicausal origin. It is believed that in the development and regulation of these processes, an important role is played by microRNA particles, which presence is ascertained in endothelial cells, atherosclerotic plaques and systemic circulation. Discovered for the first time over 20 ...

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