Tumor cells are malignant derivatives of normal cells. There are characteristic differences in the mechanophysical properties of normal and tumor cells, and these differences stem from the changes that occur in the cell cytoskeleton during cancer progression. There is a need for viable whole blood processing techniques for rapid and reliable tumor cell detection that do not require tagging. Mic...

Fibroblasts, which play an important role in biological seal formation and maintenance, determine the long-term success of percutaneous implants. In this study, well-defined microporous structures with micropore diameters of 10-60 µm were fabricated by microelectromechanical systems and their influence on the fibroblast functionalities was observed. The results show that the microporous structu...

We introduce a micro-biochemical administration module (BAM) for generating chemical gradients for use in axonal guidance studies. The device is designed to be simple to use, require minimal packaging, and be operated using only a pipette. A passive pumping mechanism is utilized to pump liquid through a SU-8 microchannel and then the micropore on the Parylene cap of the microchannel. The achie...

The study of 26 microporous carbons with average pore widths Lo between 0.7 and 1.8 nm shows that the volume-related capacitance Cmi(F cm) in the organic electrolyte (C2H5)4NBF4/acetonitrile is an inverse function of the average micropore width Lo. This means that for a given micropore volume Wo, the gravimetric capacitance C(F g) is larger for carbons with smaller pores due to the higher surfa...

The orientation transition from perpendicular to parallel alignment of PEO cylindrical domains of PEO-b-PMA(Az) films has been demonstrated by extruding the block copolymer (BCP) solutions through a micropore of a plastic gastight syringe. The parallelized orientation of PEO domains induced by this micropore extrusion can be recovered to perpendicular alignment via ultrasonication of the extrud...

The adsorption of gases on microporous carbons is still poorly understood, partly because the structure of these carbons is not well known. Here, a model of microporous carbons based on fullerene-like fragments is used as the basis for a theoretical study of Ar adsorption on carbon. First, a simulation box was constructed, containing a plausible arrangement of carbon fragments. Next, using a ne...

Sol-gel modification of mesoporous alumina membranes is a very successful technique to improve gas separation performance. Due to the formed microporous top layer, the membranes show activated transport and molecular sieve-like separation factors. This paper concentrates on the mechanism of activated transport (also often referred to as micropore diffusion or molecular sieving). Based on a theo...

Adsorption-induced deformation of a monolithic, synthetic carbon of clearly distinguishable micro- and mesoporosity was analyzed by in situ dilatometry with N2 (77 K), Ar (77 K), CO2 (273 K), and H2O (298 K). A characteristic nonmonotonic shape of the strain isotherm showing contraction of the sample at initial micropore adsorption followed by expansion toward completion of micropore filling wa...