نتایج جستجو برای: microemulsion based gels

تعداد نتایج: 2955132  

2012
USAMA FARGHALY ALY

Diabetes mellitus is one of the metabolic disorders that impedes normal steps of wound healing process. Recently, statins have been shown to have anticoagulant, immunosuppressive and antiproliferative effects that could conceivably affect wound healing or the risk of wound complications after surgery or injury. The objective of the present study was to develop formulations of Atorvastatin in di...

2011
STEFAN DIMA MARIA POPESCU

The purpose of this study was to investigate microemulsions as delivery systems for diclofenac sodium (DS). Microemulsion systems were composed of: soybean oil, nonionic surfactants (Brij 58 and Span 80), and different alcohols: ethanol, and 1-buthanol as cosurfactant. The optimum surfactant: cosurfactant (S:CoS) weight ratios and microemulsion areas were detected by the aid of ternary phase di...

2012
Xiao-Yue Xuan Yu-Ling Cheng Edgar Acosta

This article introduces the formulation of alcohol-free, lecithin microemulsion-based gels (MBGs) prepared with gelatin as gelling agent. The influence of oil, water, lecithin and hydrophilic and lipophilic additives (linkers) on the rheological properties and appearance of these gels was systematically explored using ternary phase diagrams. Clear MBGs were obtained in regions of single phase m...

2002
J. O. RADLER S. RADIMAN A. DE VALLERA C. TOPRAKCIOGLU

We have investigated by small-angle neutron scattering (SANS) the ternary system containing water, alkane and the surfactant mixture benzyltetradecyldimethylammonium chloride and tetradecyltrimethylammonium bromide, which we have found to form a cubic liquid crystalline phase. A contrast variation experiment with equal volume fractions of water and oil showed three Bragg reflections varying in ...

Journal: :Acta biomaterialia 2013
Elinor Josef Karnit Barat Iris Barsht Meital Zilberman Havazelet Bianco-Peled

Many vitamins, bioactive lipids and over 40% of newly developed drugs are hydrophobic, and their poor water solubility limits their delivery using conventional formulations. In this work we investigated a composite gel system formulated from microemulsions embedded in alginate hydrogels, and showed that it is capable of loading several hydrophobic compounds with a wide range of aqueous solubili...

Journal: :Anais da Academia Brasileira de Ciencias 2015
Muhammad Naeem Nisar Ur Rahman Guilherme D Tavares Sávio F Barbosa Nádia B Chacra Raimar Löbenberg Muhammad K Sarfraz

Flurbiprofen, a potent nonsteroidal anti-inflammatory drug, is widely used for relief of pain in patients suffering from rheumatic diseases, migraine, sore throat and primary dysmenorrheal. However, this drug has many gastrointestinal side effects produced by its oral administration, such as gastric bleeding and peptic ulcer. These effects were responsible for non-compliance among patients, whi...

Journal: :Biotechnology progress 1999
Fadnavis Koteshwar

An unusual phenomenon is observed for gelatin solutions (1.7-6.8%) in the microemulsion system of 0.3 M bis(2-ethylhexyl)sulfosuccinate sodium salt in isooctane and 14.5% distilled water. Highly viscous gels obtained at temperatures above 30 degreesC become free-flowing liquids at low temperatures (5-10 degreesC). This reversible temperature-dependent sol-gel transition phenomenon is used to im...

Journal: :Expert opinion on drug delivery 2005
Sudaxshina Murdan

In the last decade, interest in physical organogels has grown rapidly with the discovery and synthesis of a very large number of diverse molecules, which can gel organic solvents at low concentrations. The gelator molecules immobilise large volumes of liquid following their self-assembly into a variety of aggregates such as rods, tubules, fibres and platelets. The many interesting properties of...

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