A disposable on-chip whole blood/plasma separator, which is able to separate plasma from whole blood by capillary movement through a bead-packed microchannel, has been designed, fabricated and characterized in this work. Various sized silica beads were packed inside a microchannel using a slurry-bump pattern that prevented the beads from passing through the microchannel. The bead-packed microch...

The model results for the velocity field of the herringbone microchannel (Figure 1) indicate that the velocity of the fluid within the herringbone was significantly lower than the 10 velocity in the base microchannel. The velocity profile in the base microchannel closely resembles the parabolic velocity profile in the straight microchannel. However, unlike the uni-directional parabolic velocity...

In this study, the finite volume method and the SIMPLER algorithm is employed to investigate forced convection and entropy generation of Cu-water nanofluid in a parallel plate microchannel. There are four obstacles through the microchannel, and the slip velocity and temperature jump boundary conditions are considered in the governing equations to increase the accuracy of modeling. The study is ...

We propose a blood coagulation testing method based on the measurement of the flow velocity near the bottom surface of a microchannel by using a surface plasmon resonance (SPR)-based microfluidic device. We were able to distinguish the coagulation ability in different human plasma samples by observing the flow velocity change caused by coagulation that occurred at an interface between a plasma ...

Three-dimensional (3D) multi-microchannel mixers can meet the requirements of different combinations according to actual needs. Rapid and simple creation of 3D multi-microchannel mixers in a “lab-on-a-chip” platform is a significant challenge in micromachining. In order to realize the complex mixing functions of microfluidic chips, we fabricated two kinds of complex structure micromixers for mu...

Convective heat transfer of MgO-water nanofluid in a microchannel heat sink is experimentally investigated in various concentrations of 0.01, 0.05, 0.1, and 0.6 wt%. The microchannel consisted of 48 parallel rectangular cross section channels with the height of 800 µm, width of 524 µm and length of 52 mm. A well stability duration (ca. 1 month) was resulted by a 180 min ultra-sonication of the ...

The transient hydrodynamics and thermal behaviors of fluid flow in open-ended vertical parallel-plate porous microchannel are investigated semi-analytically under the effect of the hyperbolic heat conduction model. The model that combines both the continuum approach and the possibility of slip at the boundary is adopted in the study. The Effects of Knudsen number , Darcy number , and thermal re...

We report a contraction-expansion array (CEA) microchannel that allows three-dimensional hydrodynamic focusing with a single sheath flow in a single-layer device. The CEA microchannel exploits centrifugal forces acting on fluids travelling along the contraction and expansion regions of the microchannel. Around an entrance of the contraction region, the centrifugal forces induce a secondary flow...

In this study, the air-side pressure drop and heat transfer performance of plate-fin and microchannel coils were tested under clean and fouled conditions. The heat exchangers were tested with two different types of dust, ASHRAE dust and Arizona Road Test Dust. The ASHRAE dust was found to have a very significant impact on the pressure drop of the microchannel heat exchanger, increasing the air-...