Congenital Zika virus infection can cause microcephaly and other severe fetal neurological anomalies (1). To inform microcephaly surveillance efforts and assess ascertainment sources, the New York State Department of Health and the New York City Department of Health and Mental Hygiene sought to determine the prevalence of microcephaly in New York during 2013-2015, before known importation of Zi...

In addition to neuromotor, cognitive, vision and hearing impairments, it is also possible observe dental occlusion maxillofacial changes in children with microcephaly diagnosis. But, how about long-term effects on the craniofacial growth development of affected by this clinical condition skeletal maturity? context, two cases teenage dizygotic twins will be presented, which one had microcephaly,...

We establish a compartmental model for Zika virus disease transmission, with particular attention paid to microcephaly, the main threat of disease. To this end, we consider separate microcephaly-related compartments affected infants, as well role asymptomatic carriers, influence seasonality and transmission through sexual contact. determine basic reproduction number corresponding time-dependent...

OBJECTIVE To provide an evidence-based update emphasizing the importance of measuring head circumference (HC) in infants, with a focus on microcephaly. QUALITY OF EVIDENCE PubMed and EMBASE (OvidSP) were searched. Search terms used were head circumference and infants and measurement; microcephaly and infants and measurement; idiopathic microcephaly and infants; and congenital microcephaly and...

OBJECTIVES There has been a growing concern over Zika virus (ZIKV) infection, particularly since a probable link between ZIKV infection during pregnancy and microcephaly in the baby was identified. The present study aimed to estimate a theoretical risk of microcephaly during pregnancy with ZIKV infection in Northeastern Brazil in 2015. METHODS Temporal distributions of microcephaly, reported ...

BACKGROUND Congenital microcephaly is the result of a disturbance in early brain development and can have multiple etiologies. Establishing background prevalence of microcephaly in Zika virus (ZIKV)-affected areas is important for improving identification of ZIKV-affected newborns. However, to date, there is limited consistent guidance for the accurate identification of microcephaly in infants ...

OBJECTIVE To estimate the risk of microcephaly in babies born to women infected by the Zika virus during pregnancy in Brazil in an epidemic between 2015 and 2016. METHODS We obtained data on the number of notified and confirmed microcephaly cases in each Brazilian state between November 2015 and October 2016 from the health ministry. For Pernambuco State, one of the hardest hit, weekly data w...

INTRODUCTION Since the end of 2014, Zika virus (ZIKV) infection has been rapidly spreading in Brazil. METHODOLOGY To analyze the possible association of yellow fever vaccine with a protective effect against ZIKV-related microcephaly, the following spatial analyses were performed, using Brazilian municipalities as units: i) yellow fever vaccination coverage in Brazilian municipalities in indiv...

Zika virus in utero is causally associated with microcephaly in infants, showed preliminary results from the first case-control study to investigate whether Zika virus infection during pregnancy can result in microcephaly. The Brazilian Ministry of Health requested that a study be undertaken to investigate the causes of the microcephaly epidemic after declaring it a national public health emerg...