The site of outflow resistance leading to elevated intraocular pressure in primary open-angle glaucoma is believed to be located in the region of Schlemm's canal inner wall endothelium, its basement membrane and the adjacent juxtacanalicular tissue. Evidence also suggests collector channels and intrascleral vessels may have a role in intraocular pressure in both normal and glaucoma eyes. Tradit...

Slide stability is key to the aerostatic guide in ultra-precise machines; thus, it has garnered plenty of attention. Macro-scale studies are commonplace, but micro- and nano-vibration issues require more Microscope vibration mainly caused by tiny changes fluid parameters lubricating gas film, which complex no verdict. In this case, slide-gas interaction should be considered. study, widely used ...

Hydrodynamic flow focusing is a seminal, easy-to-use technology for micro- and nanodroplet generation. It is characterized by the co-axial focusing of two (or more) immiscible liquid streams forced through a small orifice. In this method, the outer continuous phase has a much higher flow velocity than the inner disperse phase. While passing through the orifice, the prevailing pressure drop and ...

This study experimentally and numerically investigates the effects of nozzle/needle distance (clearance) supply pressure on single phase compressible gas flow in a micro orifice with needle restriction, which play important roles many engineering applications such as cryogenic cooling MEMS (microelectromechanical systems) device cooling. Nitrogen was used working fluid at pressures ranging from...

The cavitation characteristics were experimentally investigated about long circular-cylindrical orifices of various throat lengths including the orifice with a trip wire. Especially, the shedding process of separated vortex cavity was examined in detail with the observation using high-speed photography. The cavitation impact was measured with an accelerometer. As a result, it is found that the ...

A reservoir-based device constructed of a completely biodegradable elastomer can enable several new implantation and insertion options for localized drug therapy, particularly in the case of urological therapies. We performed an in vitro performance evaluation of an implantable, bio-resorbable device that supplies short-term controlled release of ciprofloxacin-HCl (CIP). The proposed device fun...

The clogging behavior of the micro-orifice under a flow accelerated condition was investigated after 500 h immersion in high-temperature water. results indicated residual area reduced to one-third its original size due deposition corrosion products. In this process, can be divided into three stages: stable stage, quick recovery and dynamic equilibrium stage. products were porous consisted many ...