نتایج جستجو برای: mice survival
تعداد نتایج: 697958 فیلتر نتایج به سال:
to investigate the effects of the two-pore-domain potassium (k2p) channel task-3 in a syngeneic murine model for malignant glioma. malignant or high-grade glioma (who grade iii and iv) are the most common and most aggressive primary brain tumors in adults. despite aggressive multimodal therapy, the outcome of patients with malignant glioma remains poor. however, recent phase i and ii trials hav...
background: pre-exposure to radiofrequency radiations of mobile phones would significantly increase the survival rate of exposed animals compared to those exposed to a lethal dose of gamma radiation alone. stimulation of the immune system is believed to be a key mechanism for the induction of this phenomenon, the so-called “adaptive response.” the immune system protects organisms against infect...
Background: Pre-exposure to radiofrequency radiations of mobile phones would significantly increase the survival rate of exposed animals compared to those exposed to a lethal dose of gamma radiation alone. Stimulation of the immune system is believed to be a key mechanism for the induction of this phenomenon, the so-called “adaptive response.†The immune system protects organisms against in...
The Bezoar, a dense material found in the stomach of wild goat, is widely used against various diseases including snakebite in traditional medicine among the southeast tribes of Iran. This study was performed to evaluate the Bezoar effect on experimental mice receiving 2% and 10% concentrations of natural crude of Echis carinatus snake venom. Various doses of Bezoar (6, 50, 100 & 200 mg/kg/i....
To investigate the effects of the two-pore-domain potassium (K2P) channel TASK-3 in a syngeneic murine model for malignant glioma. Malignant or high-grade glioma (WHO grade III and IV) are the most common and most aggressive primary brain tumors in adults. Despite aggressive multimodal therapy, the outcome of patients with malignant glioma remains poor. However, recent phase I and II trials hav...
Background: Candida albicans is one of the most important opportunistic pathogens that suppress immunologic mechanisms of the host. It is speculated that structural and secretory proteins of C. albicans have immunomodulatory effects in cancer. Objective: To evaluate the effects of C. albicans structural and secreted proteins on intratumoral CD4/CD8 ratio as well as the survival rate in BALB/c t...
Background: Several reports indicate that the probiotics can increase body resistance against malignant tumors. The aim of this study is to evaluate the effect of Lactobaci-llus reuteri Persian type culture collection (PTCC) 1655 in preventing tumor growth, improving weight and survival rate in mice with breast cancer.Methods: Twenty mice, the BALB/c at six weeks age, weighing approximately 17 ...
Background and purpose: Hypoxia occurs especially in heart diseases and could lead to death. Compounds with antioxidant activity could display antihypoxic property. Sambucus ebulus (SE) and Myrtus communis (Myrtle) are well known plants with distinctive antioxidant activities. To the best of our knowledge there are no reports on their antihypoxic activities. Materials and methods: Protective e...
background: melanoma progression and metastasis is suggested to be mediated by increased accumulation of myeloid derived suppressor cells. various chemotherapeutic drugs such as 5-fluorouracil in single low concentration have the capacity, at least in part, to reverse tumor progression by reducing myeloid derived suppressor cellsmediated immunosuppression. objective: to assess whether multiple ...
Introduction: The hypoxic state, in which experimental animals were subjected to an atmosphere of 5% O2 and %95 N2, has been used to screen agents for possible cerebral protection by measuring their ability to prolong survival time in mice exposed to hypoxia. Researchers showed that rimonabant and AM251 allosteric potentiate all but the β1 subunit containing GABAA receptors at nM...
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