there are morphological and reproductive physiological differences between swamp buffalo (bubaluscarabanensis) and river buffalo (bubalus bubalis). the development of fetus weight and fetus biometry wasreported in river buffalo and other animals but not in swamp buffalo. the aim of this study was to describethe inherent variability in fetus related measurements during swamp buffalo pregnancy. t...

side effects of ciprofloxacin (cpfx), a widely used broad spectrum antibiotic with fluoroquinolone core, have been reported in different organs. in the present study we sought to elucidate the impact of ciprofloxacin on sperm chromatin integrity and sperm dna damage using aniline blue and acridine orange technique, respectively. the fertility potential in male mice was also evaluated. nmri male...

Previous studies have shown that antibodies to cubulin, a receptor on the yolk sac that binds high density lipoproteins (HDL) and cobalamin, induce fetal abnormalities. Mice with markedly low concentrations of plasma HDL-cholesterol (HDL-C) give birth to healthy pups, however. To establish whether maternal HDL-C has a role in fetal development, sterol metabolism was studied in the fetus and ext...

BACKGROUND Methamphetamine (MA) is one of most common illicit drugs which were reported that nearly half of MA consumers are women. MA can cross through placenta and affects pregnancy and fetus development. OBJECTIVE Our aim was to evaluate effects of injected MA on crown-rump length, head and placental circumference, body weight, histological changes and apoptosis in fetus. MATERIALS AND M...

Abstract Objective: Pregnancy is an immunological paradox where the maternal immune system develops tolerance to semi-allogeneic fetus yet a sensitizing event that detrimental subsequent organ transplantation. Humoral sensitization by pregnancy in WT mice prevents anti-CD154-mediated matched allograft. In contrast, lacking secreted immunoglobulins (mIgM −/−AID −/−; SIgKO) permitted anti-CD154 m...

introduction: stem cell biology has been the subject of much recent discussion. embryonic stem (es) cells, derived from the inner cell mass of the blastocyst stage of early mammalian embryos are expected to become a powerful tool in future regenerative medicine and developmental biology due to their capacity of self-renewal and pluripotency. in the present study, the ultrastructural development...

introduction: among the components of the extracellular matrix (ecm) and basement membrane (bm), laminitis heterotrimeric glycoprotein (laminin) and collagen type iv are the most important. in a previous study we have examined the role of collagen type iv in the developing lens capsule. the present study aims to determine the appearance and distribution of laminin in the bm and ecm of lenses du...

Retinoic acid is like a steroid hormone that plays a role in embryo formation, proliferation of spermatogonia cells, ephitelial cells differentiation and organogenesis. Retinoic acid can influences seminiferous tubule formation during embryonic testis development and also play a role in the regulation of ovarian function and female reproductive tract by suppressing the hormones FSH receptor exp...

Metronidazole is used to treat trichomoniasis, bacterial vaginosis, and other diseases. There are controversy aspects about its teratogenicity. A teratogenic agent can alter morphology or subsequent function of the fetus. The aim of this study was to examine an alternative method for the recognition of the mechanism or the bimolecular potential changes in mice fetus caused by Metronidazole usin...