نتایج جستجو برای: methylpyrrolidone

تعداد نتایج: 71  

2015
Paul M. Osterberg Jeffry K. Niemeier Christopher J. Welch Joel M. Hawkins Joseph R. Martinelli Thomas E. Johnson Thatcher W. Root Shannon S. Stahl

Applications of aerobic oxidation methods in pharmaceutical manufacturing are limited in part because mixtures of oxygen gas and organic solvents often create the potential for a flammable atmosphere. To address this issue, limiting oxygen concentration (LOC) values, which define the minimum partial pressure of oxygen that supports a combustible mixture, have been measured for nine commonly use...

Journal: :IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 2019

Journal: :The Journal of biological chemistry 2011
Chafik Ghayor Rita M Correro Katrin Lange Lindsay S Karfeld-Sulzer Klaus W Grätz Franz E Weber

Regulation of RANKL (receptor activator of nuclear factor κB ligand)-induced osteoclast differentiation is of current interest in the development of antiresorptive agents. Osteoclasts are multinucleated cells that play a crucial role in bone resorption. In this study, we investigated the effects of N-methylpyrrolidone (NMP) on the regulation of RANKL-induced osteoclastogenesis. NMP inhibited RA...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2002
Jean-Paul Payan Dominique Beydon Jean-Paul Fabry Isabelle Boudry Benoit Cossec Elisabeth Ferrari

This study evaluated the toxicokinetics of N-[(14)C]methylpyrrolidone ([(14)C]NMP) after intravenous administration (0.1, 1, 10, 100, and 500 mg/kg, in saline solution) or topical application (20 and 40 micro l/cm(2); 10 cm(2), neat) in haired male Sprague-Dawley rats. Whatever the dose, unchanged NMP was intensively distributed into the body with a volume of distribution of 69% of body weight....

Journal: :Fizika tverdogo tela 2021

The effect of temperature on the polarization luminescence colloidal system MoS2 nanodots in n-methylpyrrolidone is studied under condition linearly polarized excitation. Nanodots are obtained by chemical exfoliation and dispersion microcrystals a liquid medium action ultrasound. photoluminescence spectrum ensemble significantly shifted towards shorter wavelengths with respect to bulk crystals,...

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