A prospective study was undertaken to find out the benefit of immunosuppressive therapy(IV methyl prednisolone followed by oral prednisolone therapy for one year along with six doses of pulse monthly IV cyclophosphamide) in children with steroid resistant nephrotic syndrome. Thirty-four children with steroid resistant nephrotic syndrome were treated with above regime. The remission of the disea...

BACKGROUND Medications with methyl-prednisolone sodium succinate containing lactose, which potentially contains traces of cow's milk proteins (CMP), could cause allergic reactions or compromise treatment of acute allergic reactions in sensitized patients. CASE PRESENTATION We describe the unusual case of a one-year-old child affected by short bowel syndrome and history of severe cow's milk al...

OBJECTIVE There are several types of treatment modalities for wrist ganglions. The aim of the study was to assess the effectiveness of cyst aspiration and methyl prednisolone acetate injection with double IV cannula rather than sharp pointed needle, as a new technique in the treatment of volar ganglia. METHODOLOGY The study involves total of 19 patients who received treatment by aspiration an...

Positive role of niacin on serum lipid profile of rats treated with glucocorticoids (GCs) has been reported. This study aims to evaluate effect of niacin on bone changes in GC-induced dyslipidemic rats. A number of 28 growing rats divided into four groups and treated as control, Methyl prednisolone (MP) group (3.5 mg/kg five days a week, SC); MPN group (MP + niacin 200 mg/kg/day orally) and MPA...

     Neuromyelitis optica (also known as Devic's disease or Devic's syndrome) is an uncommon disorder in pediatric age group, and is characterized by acute or subacute optic neuritis and transverse myelitis. Here we report an 11- year- old female child with relapsing Neuromyelitis optica (NMO) confirmed by positive NMO- IgG antibody and had clinical recovery with high dose methyl prednisolone t...

PURPOSE The purpose of this study is to report a case of atypical serpiginous choroiditis presenting with disc edema and exudative retinal detachment, treated successfully with intravenous methyl prednisolone. METHODS A 45-year-old male patient presented with sudden decrease of vision in his left eye. On examination, left eye showed disc edema, exudative retinal detachment, and active serpigi...

Introduction: Osteoarthritis of the knee has been the most common form of arthritis encountered by clinicians today. Conservative modalities such as non steroidal anti inflammatory medications and intra articular corticosteroid have been employed to ameliorate the symptoms and delay total knee arthroplasty. In the past Corticosteroids have had an important role to play for decades in effective,...