Skeletal involvement is the second most common site of metastases after lymph nodal metastases in patients with prostate cancer. The skeletal metastases from prostate cancer are osteoblastic in nature and show increased tracer avidity on the bone scan. Focal tracer avid lesion in skeleton especially in skull requires the careful examination by further investigation. The patients with skull meta...

A 76-year-old man with symptomatic bone metastases from castrationresistant prostate cancer underwent Radium-223-dichloride (Ra-223) therapy. Before Ra-223 therapy, he had normal peripheral blood cell counts. Ra-223 therapy relieved his shoulder and low back pain. The elevation of the serum prostate-specific antigen (PSA), doubling every month during Ra-223 therapy, suggested a PSA flare or rel...

Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1)  and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck lymph node metastases of thyroid PTC showing SCD. The patient (21-years) presented wit...

  This study was done in research institute of nuclear medicine from 1988-1992 for evaluation of the value of serum thyroglobulin level in comparison with 1-131 whole body scan (1-131 WBS) in patients with differentiated thyroid carcinoma. 204 patients who had total or near total thyroidectomy treated with 1-131 were evaluated in this study. Out of 204 patients 136 di...

Distant metastases are rare during the course of ovarian carcinoma. Ovarian epithelial adenocarcinomas rarely metastasize to the skin which is seen in less than 4% of patients. It usually presents as subcutaneous nodules and, less commonly, as inflammatory metastases which mimic cellulitis or viral or bacterial skin infections. The histology in most of the tumours is grade 1 or 2 serous p...

Metastatic skin cancer is a rare complication of internal malignancies.  Patients who develop cutaneous metastases rarely present with a zosteriform distribution.  Herein, we describe a 65-year-old woman with a prior history of breast cancer in whom zosteriform metastases developed along her left T8-9 abdominal dermatomes.

adenoid cystic carcinoma of the lung is a relatively rare, slow growing lung neoplasm. metastases outside the lung are uncommon. herein, we have reported the case of a patient who presented with a large mass in the right lower lobe of her lung. bronchial biopsy revealed features suggestive of adenoid cystic carcinoma of the lung with a predominant cribriform architecture. ct abdomen showed feat...

Background: To retrospectively describe imaging characteristics of liver metastases on fused FDG-PET/ MRI data sets and to compare the diagnostic accuracy of MRI and fused FDG-PET/MRI data sets for the detection of liver metastases in patients undergoing systemic anticancer treatment. Materials and Methods: 43 oncological patients (mean age: 56+/- 11 years) were investigated by FDG-PET...

we present a rare case with history of neurological symptoms due to multiple brain metastases and no urological symptoms. during patient evaluation for primary tumor, transitional cell carcinoma (tcc) of left renal pelvis was found. the patient underwent gamma knife stereotactic radio-surgery for the metastatic brain lesions. radical nephroureterectomy was performed, and a 4-cycle course of pac...