The metabolic tumor volume (MTV) is the volume of metabolically-active tumor on PET/CT. Although its potential clinical value has been investigated in many cancers, its routine use has been hampered by the delineation method used to calculate the tumor volume. This may be especially difficult for fuzzyPET images. Previous studies have used a lot of approaches for delineation of tumor volume; ho...

Introduction and Aim: Recently, in an ancillary study of FOLL12 trial (NCT02063685), total Metabolic Tumor Volume (tMTV) assessed before treatment has been demonstrated to be independent predictor PFS patients receiving frontline immune chemotherapy (1). During the segmentation procedure, it observed that frequently spleen MTV (sMTV) heavily influenced tMTV value, particularly case diffuse upta...

UNLABELLED PET can be used to monitor response during chemotherapy and assess biologic target volumes for radiotherapy. Previous simulation studies have shown that the performance of various automatic or semiautomatic tumor delineation methods depends on image characteristics. The purpose of this study was to assess test-retest variability of tumor delineation methods, with emphasis on the effe...

PURPOSE The ability to determine the spatial and metabolic distribution of prostate cancer is essential in assessing initial stage, prognosis, and treatment efficacy. Current markers of tumor progression such as prostate-specific antigen (PSA) do not provide spatial information about tumor extent or regions of high metabolic activity. EXPERIMENTAL DESIGN This study used the androgen-dependent...

Purpose: The ability to determine the spatial and metabolic distribution of prostate cancer is essential in assessing initial stage, prognosis, and treatment efficacy. Current markers of tumor progression such as prostate-specific antigen (PSA) do not provide spatial information about tumor extent or regions of high metabolic activity. Experimental Design: This study used the androgendependent ...

background: tumor lysis syndrome caused by widespread tumor cell damage may lead to electrolyte imbalances and express as metabolic disturbance causing clinical abnormalities. patients and methods: all patients younger than 16 years with documented malignancy candidate for chemotherapy, in hamedan province of iran were enrolled. results: out of 69 cancer patients the laboratory form of tumor ly...

BACKGROUND Metabolic tumor volume assessment using positron-emission tomography [PET] may be of interest for both target volume definition in radiotherapy and monitoring response to therapy. It has been reported, however, that metabolic volumes derived from images of metabolic rate of glucose (generated using Patlak analysis) are smaller than those derived from standardized uptake value [SUV] i...