نتایج جستجو برای: mesenchymal stem cells mice

تعداد نتایج: 1765570  

Background & Aims: The positive effect of mesenchymal stem cells in healing of various types of tissue damage such as burn has been reported. The therapeutic potential effects of mesenchymal stem cells influenced by certain agonists from their surface called Toll like receptor (TLR) can be modified into proinflammatory and anti-inflamation phenotypes. It is believed that modification of phenoty...

Journal: :iranian biomedical journal 0
mehri fayazi mojdeh salehnia saeideh ziae

background: the aim of this study was to investigate the percentage of the stem cells population in human endometrial tissue sections and cultured cells at fourth passage. methods: human endometrial specimens were divided into two parts, one part for morphological studies and the other part for in vitro culture. full thickness of human normal endometrial sections and cultured endometrial cells ...

Ahmad Ghorbani Reza Shafiee-Nick Seyyed Abbas Zojaj

Background  In recent years, many researchers haveattempted to cure diabetes by using stem cells technology. Stem cells from different sources have capabilityto differentiateinto insulin producing cells (IPCs) by different methods. The obstaclesof these methods aretheirexpensive materials and complexity ofmethodswhichare practicallydisadvantagesfor producing enough transplantableIPCs that can ...

Journal: :iranian biomedical journal 0
fatemeh amiri sedigheh molaei marzie bahadori fatemeh nasiri mohammad reza deyhim mohammad ali jalili

background: mesenchymal stem cells (mscs) have been recently received increasing attention for cell-based therapy, especially in regenerative medicine. however, the low survival rate of these cells restricts their therapeutic applications. it is hypothesized that autophagy might play an important role in cellular homeostasis and survival. this study aims to investigate the regenerative potentia...

Journal: :iranian biomedical journal 0
محمدعلی شکرگزار mohammad ali shokrgozar مریم فتاحی maryam fattahi شاهین بنکدار shahin bonakdar ایرج راگردی کاشانی iraj ragerdi محمد مجیدی mohammad majidi نوشین حقیقی پور nooshin haghighipour وحید بیاتی

background: wound healing of burned skin remains a major goal in public health. previous reports showed that the bone marrow stem cells were potent in keratinization and vascularization of full thickness skin wounds. methods: in this study, mesenchymal stem cells were derived from rat adipose tissues and characterized by flowcytometry. staining methods were used to evaluate their differentiatio...

Journal: :apadana journal of clinical research 2012
fakher rahim najmaldin saki seyed hadi mousavi masoud soleimani gholamreza khamisipour

human mesenchymal stem cells (hmscs), which also called mesenchymal stromal cells, are multipotent stem cell. human mscs typically are positive for the surface markers cd44, cd73, cd90, cd105, cd106, and also negative for hematopoietic markers cd34 and cd45.these cells can be isolated from postnatal bone marrow, adipose tissue, placenta, and scalp tissue, as well as from various fetal tissues. ...

Journal: :iranian journal of biotechnology 2007
somaieh kazemnejad abdolamir allameh masoud soleimani ahmad gharehbaghian naser amirizadeh

in this present study, we examined the differentiation potential of human bone marrow derived mesenchymal stem cells (hbmscs) into hepatocytes on a three-dimentional (3d) nanofibrous scaffold formed by poly (ε-caprolactone) (pcl), collagen and polyethersulfone (pes). the nanofiber was prepared by the electrospining technique. hbmscs were isolated using combining gradient density centrifugation ...

Journal: :cell journal 0
mehdi kadivar neda memari pezhman fard-esfahani

background: the aim of this study was optimization of the polyfect gene delivery method of pcdna3.1 expression vector transfected with the mouse pdx-1 gene in three different kinds of mesenchymal stem cells and hepa cells as well as comparison of transfection efficiency leading to expression of the mentioned gene in the cell types used. materials and methods: rat bone marrow-derived mesenchymal...

Journal: :nanomedicine journal 0
amir doustgani department of chemical engineering, university of zanjan, zanjan, iranسازمان اصلی تایید شده: دانشگاه زنجان (zanjan university)

objective(s): electrospun nanofibrous mats of poly(lactic acid) (pla) and nanohydroxyapatite (nano-ha) were prepared and proliferation and differentiation of mesenchymal stem cells on the prepared nanofibers were investigated in this study. materials and methods: pla/nano-ha nanofibers were prepared by electrospinning. the effects of process parameters, such as nano-ha concentration, distance, ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علوم پایه دامغان 1389

هم کشتی سلول های بنیادی با یکدیگر دریچه های جدیدی را فرا روی محققین علم سلول درمانی گشوده است. با این روش میتوان سبب بهبود شرایط کشت و تمایز بهتر سلول های بنیادی شد. فاکتورهای رشد عصبی (neurotrophic factors,ntfs)، مولکول هایی هستند که نقش های بسیار حیاتی در بقا، تکثیر و تمایز سلول های بنیادی دارند. هدف از این تحقیق ارزیابی بیان فاکتورهای نوروتروفیک (‎‎‎‎gdnf‎‎، ‎bdnf‎، ‎‎‎cntf‎،nt3) و سرعت تکثی...

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