Amenorrhea and menorrhagia are opposites and not in any way related to each other. However, the main goal of endometrial ablative therapy in menorrhagia is to establish amenorrhea. Therefore, it is obvious that we spend some words on this subject. Menorrhagia is an important problem in premenopausal women visiting their gynaecologist or general practitioner. Treatment of menorrhagia is diverse:...

increased serum F.D.P. levels in women with clinically significant menorrhagia, as compared with those in women without abnormal menstrual symptoms. Further studies being undertaken indicate that raised serum F.D.P. levels found in women with menorrhagia are often associated with increased levels of fibrin monomer complexes in the blood. Thus raised serum F.D.P. levels in women complaining of m...

Local endometrial aberrations are thought to be the major contributing factor to essential menorrhagia. Here we have examined the role of endometrial angiogenesis, the growth of new blood vessels, in essential menorrhagia. Our study tested two hypotheses: firstly that angiogenesis is disturbed in the endometrium of women with menorrhagia; and secondly that when menstrual blood loss is decreased...

The levonorgestrel-releasing intrauterine system (LNG-IUS) has proven to be the most effective medical treatment in reducing the amount of menstrual blood loss. However, the molecular mechanisms underlying menorrhagia and/or accounting for the therapeutic effect of the LNG-IUS are still obscure. In this study, we used immunohistochemistry to compare the distribution of sex steroid receptors and...

Hypovitaminosis A was found to be an important cause of menorrhagia, and a statistically significant difference between the fasting serum vitamin A values of healthy controls and patients with menorrhagia was noted. Vitamin A is a co-factor of 3 beta-dehydrogenase in steroidogenesis and deficiencies of this vitamin may result in impaired enzyme activity. The level of endogenous 17 beta-oestradi...

This study examined the effect of menorrhagia on the quality of life (QOL) of adolescents. We used data from a survey of 45 adolescents. Using the Pictorial Blood Assessment Chart (PBAC) and a PBAC score of > or =100 we identified adolescents likely to have menorrhagia. Our statistical analysis indicated that menorrhagia adversely affects the QOL of adolescents. In this article we discuss the i...

increased serum F.D.P. levels in women with clinically significant menorrhagia, as compared with those in women without abnormal menstrual symptoms. Further studies being undertaken indicate that raised serum F.D.P. levels found in women with menorrhagia are often associated with increased levels of fibrin monomer complexes in the blood. Thus raised serum F.D.P. levels in women complaining of m...

STUDY QUESTION Is the presence of adenomyosis associated with menorrhagia? SUMMARY ANSWER There was no significant association between adenomyosis and menorrhagia, but there was a significant positive correlation between the severity of adenomyosis on ultrasound and the amount of menstrual loss estimated using pictorial blood loss assessment charts. WHAT IS KNOWN ALREADY There is no consens...

BACKGROUND Menorrhagia is objectively defined as blood loss greater than 80 ml or menstrual period lasting longer than 7 days. Dysfunctional uterine bleeding is responsible for 80% cases of Menorrhagia. Objective of this study was to find out the endometrial pathology and usefulness of hysterocopic directed endomentrial sampling in patient having menorrhagia in premenopausal age group. METHOD...