BACKGROUND AND PURPOSE Distribution of lesions or involvement of specific anatomic sites can suggest the diagnosis of disease. The purpose of this study was to investigate what diseases affect both middle cerebellar peduncles (MCPs) and to evaluate other MR features for differential diagnosis. METHODS MR findings of 27 patients (14 male and 13 female; age range, 4-77 years [mean, 48.5 years])...

AIM To evaluate the diagnostic value of telomerase expression in intracranial tumours. METHODS 98 surgical specimens from different neoplasms were analysed by the telomeric repeat amplification protocol (TRAP) and the presence of telomerase compared with the histological diagnosis and the proliferation index. RESULTS A high degree of positivity for telomerase activity was found in glioblast...

Solitary fibrous tumors (SFTs), are a group of rare, spindle-cell derived fibrous neoplasms most commonly found in the thoracic (pleural) cavity (80%). However, it has been described that SFTs can affect a wide range of anatomic sites outside the pleura, including retroperitoneum, meningeal, nasal cavity and others (20%). Solitary fibrous tumors are usually described in patients between 40 and ...

absract intracranial invasion of cellular blue nevus (cbn) from the skin is extremely rare and such a condition with malignant transformation is even rarer. a case of meningeal melanoma with malignant transformation which was derived from an ota nevus is presented in this report. a21-year-old man with a neurocutaneous syndrome since childhood was referred with headache and mild left hemiparesia...

intracranial hemangiopericytomas (hpc) are rare vascular tumors. they account for 0.4% of primary central nervous system tumors. hpc is more commonly located supratentorially and tends to occur in a younger age group, with average age at presentation of 38–42 years. the tumor was found throughout the entire cns, usually superficially and closely related to the meninges. moreover, they have a st...

Meningeal myelomatosis is a rare feature of multiple myeloma. We report a case of IgG-kappa myeloma presenting as bilateral intracranial extraaxial masses.

Meningeal melanocytoma is a rare pigmented tumor of the leptomeningeal melanocytes. This rare entity results in diagnostic difficulty in imaging unless clinical and histopathology correlation is performed. In this case report, we describe a case of meningeal melanocytoma of the cervical region presenting with superficial siderosis. Extensive neuroradiological examination is necessary to locate ...

The distribution of S-100 proteins was examined in 98 pediatric brain neoplasms with rabbit antiserum to S-100 protein, utilizing the peroxidase-antiperoxidase (PAP) immunohistochemical technique. Positive cytoplasmic immunoreactivity was present in 22 of 24 astrocytomas, both oligodendrogliomas, eight of 13 ependymomas, all 11 choroid plexus tumors, all nine schwannomas, two of six meningiomas...

Schwannomas and grade I meningiomas are non‑metastatic neoplasms that share the common mutation of gene NF2. They usually appear in neurofibromatosis type 2 patients. Currently, there is no drug treatment available for both tumors, thus the use of wide expression technologies is crucial to identify therapeutic targets. Affymetrix Human Gene 1.0 ST was used to test global gene expression in 22 m...